A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers
Currently, gut microbiome profiling largely relies on next-generation sequencing, which is slow and expensive. Here, the authors develop a low-cost, paper-based synthetic biology platform that allows species-specific quantification of bacterial mRNAs and clinically relevant host biomarkers.
Main Authors: | Melissa K. Takahashi, Xiao Tan, Aaron J. Dy, Dana Braff, Reid T. Akana, Yoshikazu Furuta, Nina Donghia, Ashwin Ananthakrishnan, James J. Collins |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05864-4 |
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