MiR-146a Regulates Inflammatory Infiltration by Macrophages in Polymyositis/Dermatomyositis by Targeting TRAF6 and Affecting IL-17/ICAM-1 Pathway

MiR-146a Regulates Inflammatory Infiltration by Macrophages in Polymyositis/Dermatomyositis by Targeting TRAF6 and Affecting IL-17/ICAM-1 Pathway

Background/Aims: The primary objective of this study was to investigate the role of miR-146a in inducing the inflammatory infiltration of macrophages in polymyositis/dermatomyositis (PM/DM) through targeting TNF receptor associated factor 6 (TRAF6), which may further down-regulate the Interleukin-17...

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Bibliographic Details
Main Authors: Yuanqin Yin, Fei Li, Jing Shi, Songlin Li, Jingjing Cai, Youhong Jiang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
PM/DM
TRAF6
IL-17
ICAM-1
Macrophage
Inflammatory
Online Access:http://www.karger.com/Article/FullText/452563

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