Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila.

Defining the molecular structure and function of synapses is a central theme in brain research. In Drosophila the Bruchpilot (BRP) protein is associated with T-shaped ribbons ("T-bars") at presynaptic active zones (AZs). BRP is required for intact AZ structure and normal evoked neurotransm...

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Bibliographic Details
Main Authors: Vanessa Nieratschker, Alice Schubert, Mandy Jauch, Nicole Bock, Daniel Bucher, Sonja Dippacher, Georg Krohne, Esther Asan, Sigrid Buchner, Erich Buchner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2759580?pdf=render