An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5

An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5

The Nucleosome Remodeling and Deacetylase (NuRD) complex is a chromatin regulatory complex that functions as a transcriptional co-repressor in metazoans. The NuRD subunit MBD3 is essential for targeting and assembly of a functional NuRD complex as well as embryonic stem cell (ESC) pluripotency. Thre...

Full description

Bibliographic Details
Main Authors: Ly-Sha Ee, Kurtis N. McCannell, Yang Tang, Nancy Fernandes, W. Rod Hardy, Michael R. Green, Feixia Chu, Thomas G. Fazzio
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Stem Cell Reports
Subjects:
NuRD
Mbd3
Wdr5
chromatin
differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117301741

Similar Items

Similar Items