Inducible Sterilization of Zebrafish by Disruption of Primordial Germ Cell Migration.

During zebrafish development, a gradient of stromal-derived factor 1a (Sdf1a) provides the directional cue that guides the migration of the primordial germ cells (PGCs) to the gonadal tissue. Here we describe a method to produce large numbers of infertile fish by inducing ubiquitous expression of Sd...

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Bibliographic Details
Main Authors: Ten-Tsao Wong, Paul Collodi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3694954?pdf=render

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