Targeted sequencing of cancer‐related genes in nasopharyngeal carcinoma identifies mutations in the TGF‐β pathway

Targeted sequencing of cancer‐related genes in nasopharyngeal carcinoma identifies mutations in the TGF‐β pathway

Abstract Approximately, 25% of nasopharyngeal carcinoma (NPC) patients develop recurrent disease. NPC may involve relatively few genomic alterations compared to other cancers due to its association with Epstein‐Barr virus (EBV). We envisioned that in‐depth sequencing of tumor tissues might provide n...

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Bibliographic Details
Main Authors: An‐Ko Chung, Chun‐Nan OuYang, Hsuan Liu, Mei Chao, Ji‐Dung Luo, Cheng‐Yang Lee, Yen‐Jung Lu, I‐Che Chung, Lih‐Chyang Chen, Shao‐Min Wu, Ngan‐Ming Tsang, Kai‐Ping Chang, Cheng‐Lung Hsu, Hsin‐Pai Li, Yu‐Sun Chang
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Cancer Medicine
Subjects:
copy number variation
mutation
nasopharyngeal carcinoma
next‐generation sequencing
TGF‐β signaling
Online Access:https://doi.org/10.1002/cam4.2429

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