Biological variation in the sizes, shapes and locations of visual cortical areas in the mouse.

Visual cortex is organized into discrete sub-regions or areas that are arranged into a hierarchy and serves different functions in the processing of visual information. In retinotopic maps of mouse cortex, there appear to be substantial mouse-to-mouse differences in visual area location, size and sh...

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Bibliographic Details
Main Authors: Jack Waters, Eric Lee, Nathalie Gaudreault, Fiona Griffin, Jerome Lecoq, Cliff Slaughterbeck, David Sullivan, Colin Farrell, Jed Perkins, David Reid, David Feng, Nile Graddis, Marina Garrett, Yang Li, Fuhui Long, Chris Mochizuki, Kate Roll, Jun Zhuang, Carol Thompson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213924
Description
Summary:Visual cortex is organized into discrete sub-regions or areas that are arranged into a hierarchy and serves different functions in the processing of visual information. In retinotopic maps of mouse cortex, there appear to be substantial mouse-to-mouse differences in visual area location, size and shape. Here we quantify the biological variation in the size, shape and locations of 11 visual areas in the mouse, after separating biological variation and measurement noise. We find that there is biological variation in the locations and sizes of visual areas.
ISSN:1932-6203