Studies on antistress activity of Curculigo Orchioides gaertn

• Main Authors: Nagendra Singh Chauhan, Kamal Shah, Prashant Kumar Gupta
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2021-01-01
• Series: Biomedical and Biotechnology Research Journal
• Subjects: adaptogen; antistress activity; curculigo orchioides; diazepam; tail suspension test
• Online Access: http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2021;volume=5;issue=2;spage=145;epage=148;aulast=Chauhan
• ISSN: 2588-9834; 2588-9842

The aim of this study was to evaluate the antistress activity of rhizomes ethanolic extract of Curculigo orchioides Gaertn in vivo, using mice with stress-induced injury. The effect of Curculigo orchioides on motor coordination, spontaneous locomotor activity, immobility time, and analgesia was evaluated in mice using standard procedure. The ethanolic extract of Curculigo orchioides at dose levels, i.e., 100 and 200 mg/kg shows pronounced antistress activity evidenced by reduced immobility time in forced swimming and tail test. It also improved motor coordination and enhanced analgesic effect compared to standard diazepam. The Curculigo orchioides was found to be a antistress activity.