Watch and wait approach in rectal cancer treatment
Introduction: The colorectal carcinoma is the most common gastrointestinal neoplasm worldwide and in Bulgaria. The choice of surgical treatment is often difficult, and organ-preserving surgery is not feasible. In borderline situations, when choosing a surgical approach is difficult, the neoadjuva...
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doaj-f929f3d4c59f469da23e2834b288f6832021-04-03T16:27:18ZengBulgarian Association of Young SurgeonsInternational Journal of Surgery and Medicine2367-699X2016-01-012110.5455/ijsm.20150819025133Watch and wait approach in rectal cancer treatment D. Penchev0S. Maslyankov1V. Kostov2 L. Dimitrova3V. Ivanova4G.Todorov5Medical University of Sofia – Medical FacultyI Surgical Department of UMHAT “Alexandrovska"Medical University of Sofia – Medical FacultyMedical University of Sofia – Department of PathologyMedical University of Sofia – Department of PathologyI Surgical Department of UMHAT “Alexandrovska"Introduction: The colorectal carcinoma is the most common gastrointestinal neoplasm worldwide and in Bulgaria. The choice of surgical treatment is often difficult, and organ-preserving surgery is not feasible. In borderline situations, when choosing a surgical approach is difficult, the neoadjuvant chemoradiotherapy may downsize the tumor and provide better results and more surgical options. If the treatment response is partial or complete, the possibility of sphincter-sparing surgery is increased. The aim of the study is to present a clinical case of a patient with rectal carcinoma, submitted to multimodal treatment. Case report: The presented patient is a 65-year old female, with disturbing symptoms and diagnosed rectal adeno- carcinoma. The patient underwent preoperative neoadjuvant treatment. After a full course of treatment, the tumor was resized and was reported an almost complete clinical response to the therapy. After the recommended period had ended, she underwent an anterior resection of the rectum. This case is an example of the potential possibilities of a multidisciplinary team in surgical oncology. Conclusions: There are certain criteria, regarding the “Watch and wait” approach in rectal carcinoma, and it subjected to a set of indications in the case of a complete or near complete response to the treatment. The current case is not the brightest example of applying this approach, but still is a case of performing a sphincter-spearing surgery, which may lead to higher quality of life of the target patient group. The ESMO guidelines for the neoadjuvant treatment of rectal adenocarcinoma are applicable in Bulgaria.http://www.scopemed.org/fulltextpdf.php?mno=193538rectal carcinomaneoadjuvant treatmentchemoradiotherapy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
D. Penchev S. Maslyankov V. Kostov L. Dimitrova V. Ivanova G.Todorov |
spellingShingle |
D. Penchev S. Maslyankov V. Kostov L. Dimitrova V. Ivanova G.Todorov Watch and wait approach in rectal cancer treatment International Journal of Surgery and Medicine rectal carcinoma neoadjuvant treatment chemoradiotherapy |
author_facet |
D. Penchev S. Maslyankov V. Kostov L. Dimitrova V. Ivanova G.Todorov |
author_sort |
D. Penchev |
title |
Watch and wait approach in rectal cancer treatment |
title_short |
Watch and wait approach in rectal cancer treatment |
title_full |
Watch and wait approach in rectal cancer treatment |
title_fullStr |
Watch and wait approach in rectal cancer treatment |
title_full_unstemmed |
Watch and wait approach in rectal cancer treatment |
title_sort |
watch and wait approach in rectal cancer treatment |
publisher |
Bulgarian Association of Young Surgeons |
series |
International Journal of Surgery and Medicine |
issn |
2367-699X |
publishDate |
2016-01-01 |
description |
Introduction:
The colorectal carcinoma is the most common gastrointestinal neoplasm worldwide and in Bulgaria. The
choice of surgical treatment is often difficult, and organ-preserving surgery is not feasible. In borderline situations, when
choosing a surgical approach is difficult, the neoadjuvant chemoradiotherapy may downsize the tumor and provide better
results and more surgical options. If the treatment response is partial or complete, the possibility of sphincter-sparing
surgery is increased. The aim of the study is to present a clinical case of a patient with rectal carcinoma, submitted to
multimodal treatment.
Case report:
The presented patient is a 65-year old female, with disturbing symptoms and diagnosed rectal adeno-
carcinoma. The patient underwent preoperative neoadjuvant treatment. After a full course of treatment, the tumor
was resized and was reported an almost complete clinical response to the therapy. After the recommended period had
ended, she underwent an anterior resection of the rectum. This case is an example of the potential possibilities of a
multidisciplinary team in surgical oncology.
Conclusions:
There are certain criteria, regarding the “Watch and wait” approach in rectal carcinoma, and it subjected
to a set of indications in the case of a complete or near complete response to the treatment. The current case is not the
brightest example of applying this approach, but still is a case of performing a sphincter-spearing surgery, which may
lead to higher quality of life of the target patient group. The ESMO guidelines for the neoadjuvant treatment of rectal
adenocarcinoma are applicable in Bulgaria. |
topic |
rectal carcinoma neoadjuvant treatment chemoradiotherapy |
url |
http://www.scopemed.org/fulltextpdf.php?mno=193538 |
work_keys_str_mv |
AT dpenchev watchandwaitapproachinrectalcancertreatment AT smaslyankov watchandwaitapproachinrectalcancertreatment AT vkostov watchandwaitapproachinrectalcancertreatment AT ldimitrova watchandwaitapproachinrectalcancertreatment AT vivanova watchandwaitapproachinrectalcancertreatment AT gtodorov watchandwaitapproachinrectalcancertreatment |
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