MOLECULAR GENETIC MARKERS AS PREDICTORS OF TUMOR RESPONSE TO NEOADJUVANT CHEMOTHERAPY FOR RECTAL CANCER

MOLECULAR GENETIC MARKERS AS PREDICTORS OF TUMOR RESPONSE TO NEOADJUVANT CHEMOTHERAPY FOR RECTAL CANCER

The review presents the mechanisms involved in the biological behavior of rectal cancer cells. The tumor response to neoadjuvant chemoradiotherapy was evaluated. The characteristics of proliferative activity, apoptosis, cell adhesion, and migration of rectal cancer cells influenced by chemotherapy w...

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Bibliographic Details
Main Authors: S. R. Altybaev, S. G. Afanasyev, M. V. Zavyalova, I. V. Stepanov, D. A. Sorokin
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2016-11-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
rectal cancer
neoadjuvant chemoradiation
tumor response
immunohistochemistry
genetic markers
Online Access:https://www.siboncoj.ru/jour/article/view/408
Description
Summary:The review presents the mechanisms involved in the biological behavior of rectal cancer cells. The tumor response to neoadjuvant chemoradiotherapy was evaluated. The characteristics of proliferative activity, apoptosis, cell adhesion, and migration of rectal cancer cells influenced by chemotherapy were described. The relationship between molecular genetic markers and prediction of response to chemoradiation in rectal cancer was shown.
ISSN:1814-4861
2312-3168

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