Specificities of Human Hepatocellular Carcinoma Developed on Non-Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue Extracts 1H-NMR Spectroscopy

Specificities of Human Hepatocellular Carcinoma Developed on Non-Alcoholic Fatty Liver Disease in Absence of Cirrhosis Revealed by Tissue Extracts 1H-NMR Spectroscopy

There is a rising incidence of non-alcoholic fatty liver disease (NAFLD) as well as of the frequency of Hepato-Cellular Carcinoma (HCC) associated with NAFLD. To seek for putative metabolic pathways specific of the NAFLD etiology, we performed comparative metabolomics between HCC associated with NAF...

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Bibliographic Details
Main Authors: Camille Teilhet, Daniel Morvan, Juliette Joubert-Zakeyh, Anne-Sophie Biesse, Bruno Pereira, Sylvie Massoulier, Pierre Dechelotte, Denis Pezet, Emmanuel Buc, Géraldine Lamblin, Michel Peoc’h, Jack Porcheron, Marie-Paule Vasson, Armando Abergel, Aicha Demidem
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Metabolites
Subjects:
hepato-cellular carcinoma
1H-NMR spectroscopy
metabolomics
cirrhosis
NAFLD
metabolites
biomarkers
glutamine synthetase
Online Access:https://www.mdpi.com/2218-1989/7/4/49

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