Felis catus gammaherpesvirus 1 (FcaGHV1) and coinfections with feline viral pathogens in domestic cats in Brazil
ABSTRACT: Felis catus gammaherpesvirus 1 (FcaGHV1) may causes an asymptomatic infection that result in an efficient transmission and subsequently dissemination of the virus in feline population. This study used molecular detection by qPCR (quantitative PCR) based on DNA polymerase gene fragment ampl...
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Universidade Federal de Santa Maria
2018-03-01
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doaj-f948ee8f2f57440cbbe5d788d939747d2020-11-25T00:10:12ZengUniversidade Federal de Santa MariaCiência Rural1678-45962018-03-0148310.1590/0103-8478cr20170480S0103-84782018000300451Felis catus gammaherpesvirus 1 (FcaGHV1) and coinfections with feline viral pathogens in domestic cats in BrazilJacqueline Kazue KurissioMarianna Vaz RodriguesSueli Akemi TaniwakiMarcelo de Souza ZanuttoClaudia FiloniMaicon Vinícius GaldinoJoão Pessoa Araújo JúniorABSTRACT: Felis catus gammaherpesvirus 1 (FcaGHV1) may causes an asymptomatic infection that result in an efficient transmission and subsequently dissemination of the virus in feline population. This study used molecular detection by qPCR (quantitative PCR) based on DNA polymerase gene fragment amplification to evaluate the occurrence of FcaGHV1 and its correlation with other feline viral pathogens, such as Carnivore protoparvovirus 1 (CPPV-1), Felid alphaherpesvirus 1 (FeHV-1), and feline retroviruses such as feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV). Of the 182 blood samples evaluated 23.6% (43/182) were positives for FcaGHV1. Approximately 37.9% (33/87) of the samples that tested positive for retrovirus were also were positive for FcaGHV1 infection (P<0.0001). Among FIV-infected samples, 49% (24/49) were positive for FcaGHV1 (P<0.0001). FcaGHV1 infection was not associated with FeLV (P>0.66) or CPPV-1 (P>0.46) coinfection. All samples were negative for FeHV-1. Male felines were significantly associated to FcaGHV1 (P<0.0001) and their risk of infection with FcaGHV1 was about of 7.74 times greater compared to females. Kittens (≤ 1year) were the least affected by FcaGHV1 infection, being verified a rate of 7.7% (4/52). Therefore, male cats over one year old and infected with FIV were considerably more likely to be infected with FcaGHV1. To our knowledge, this is the first study to report the occurrence and molecular detection of FcaGHV1 infection in domestic cats in Brazil and in South America.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000300451&lng=en&tlng=engammaherpesvirusherpesvirusfeline pathogeninfectious diseasesdiagnosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jacqueline Kazue Kurissio Marianna Vaz Rodrigues Sueli Akemi Taniwaki Marcelo de Souza Zanutto Claudia Filoni Maicon Vinícius Galdino João Pessoa Araújo Júnior |
spellingShingle |
Jacqueline Kazue Kurissio Marianna Vaz Rodrigues Sueli Akemi Taniwaki Marcelo de Souza Zanutto Claudia Filoni Maicon Vinícius Galdino João Pessoa Araújo Júnior Felis catus gammaherpesvirus 1 (FcaGHV1) and coinfections with feline viral pathogens in domestic cats in Brazil Ciência Rural gammaherpesvirus herpesvirus feline pathogen infectious diseases diagnosis |
author_facet |
Jacqueline Kazue Kurissio Marianna Vaz Rodrigues Sueli Akemi Taniwaki Marcelo de Souza Zanutto Claudia Filoni Maicon Vinícius Galdino João Pessoa Araújo Júnior |
author_sort |
Jacqueline Kazue Kurissio |
title |
Felis catus gammaherpesvirus 1 (FcaGHV1) and coinfections with feline viral pathogens in domestic cats in Brazil |
title_short |
Felis catus gammaherpesvirus 1 (FcaGHV1) and coinfections with feline viral pathogens in domestic cats in Brazil |
title_full |
Felis catus gammaherpesvirus 1 (FcaGHV1) and coinfections with feline viral pathogens in domestic cats in Brazil |
title_fullStr |
Felis catus gammaherpesvirus 1 (FcaGHV1) and coinfections with feline viral pathogens in domestic cats in Brazil |
title_full_unstemmed |
Felis catus gammaherpesvirus 1 (FcaGHV1) and coinfections with feline viral pathogens in domestic cats in Brazil |
title_sort |
felis catus gammaherpesvirus 1 (fcaghv1) and coinfections with feline viral pathogens in domestic cats in brazil |
publisher |
Universidade Federal de Santa Maria |
series |
Ciência Rural |
issn |
1678-4596 |
publishDate |
2018-03-01 |
description |
ABSTRACT: Felis catus gammaherpesvirus 1 (FcaGHV1) may causes an asymptomatic infection that result in an efficient transmission and subsequently dissemination of the virus in feline population. This study used molecular detection by qPCR (quantitative PCR) based on DNA polymerase gene fragment amplification to evaluate the occurrence of FcaGHV1 and its correlation with other feline viral pathogens, such as Carnivore protoparvovirus 1 (CPPV-1), Felid alphaherpesvirus 1 (FeHV-1), and feline retroviruses such as feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV). Of the 182 blood samples evaluated 23.6% (43/182) were positives for FcaGHV1. Approximately 37.9% (33/87) of the samples that tested positive for retrovirus were also were positive for FcaGHV1 infection (P<0.0001). Among FIV-infected samples, 49% (24/49) were positive for FcaGHV1 (P<0.0001). FcaGHV1 infection was not associated with FeLV (P>0.66) or CPPV-1 (P>0.46) coinfection. All samples were negative for FeHV-1. Male felines were significantly associated to FcaGHV1 (P<0.0001) and their risk of infection with FcaGHV1 was about of 7.74 times greater compared to females. Kittens (≤ 1year) were the least affected by FcaGHV1 infection, being verified a rate of 7.7% (4/52). Therefore, male cats over one year old and infected with FIV were considerably more likely to be infected with FcaGHV1. To our knowledge, this is the first study to report the occurrence and molecular detection of FcaGHV1 infection in domestic cats in Brazil and in South America. |
topic |
gammaherpesvirus herpesvirus feline pathogen infectious diseases diagnosis |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000300451&lng=en&tlng=en |
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