Synthesis, Solution, and Structural Characterization of Tetrahydrofuranyl-2,2-Bisphosphonic Acid Disodium Salt
Bisphosphonates are biologically relevant therapeutics for bone disorders and cancer. Reaction of γ-chlorobutyric acid, phosphorus acid, and phosphorus trichloride without the use of solvent gave the tetrahydrofuranyl-2,2-bisphosphonate sodium salt (Na2H2L). The Na2H2L was isolated, characterized in...
Main Authors: | Elena Maltezou, Marios Stylianou, Sudeshna Roy, Chryssoula Drouza, Anastasios D. Keramidas |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2010-01-01
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Series: | Bioinorganic Chemistry and Applications |
Online Access: | http://dx.doi.org/10.1155/2010/563875 |
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