Tregalizumab - a monoclonal antibody to target regulatory T cells

Tregalizumab - a monoclonal antibody to target regulatory T cells

Regulatory T cells (Tregs) represent a subpopulation of CD4+ T cells, which are essential for the maintenance of immunological tolerance. The absence or dysfunction of Tregs can lead to autoimmunity and allergies. The restoration of functional Tregs and/or Treg cell numbers represents a novel and at...

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Bibliographic Details
Main Authors:	Martin eKönig, Faiza eRharbaoui, Silke eAigner, Benjamin eDälken, Jörg eSchüttrumpf
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-01-01
Series:	Frontiers in Immunology
Subjects:	Autoimmunity Monoclonal antibody Rheumatoid arthritis regulatory T cells CD4 T cells
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00011/full

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