Engineered Liver-On-A-Chip Platform to Mimic Liver Functions and Its Biomedical Applications: A Review

Hepatology and drug development for liver diseases require in vitro liver models. Typical models include 2D planar primary hepatocytes, hepatocyte spheroids, hepatocyte organoids, and liver-on-a-chip. Liver-on-a-chip has emerged as the mainstream model for drug development because it recapitulates t...

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Bibliographic Details
Main Authors: Jiu Deng, Wenbo Wei, Zongzheng Chen, Bingcheng Lin, Weijie Zhao, Yong Luo, Xiuli Zhang
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/10/10/676