Spider Silk for Tissue Engineering Applications
Due to its properties, such as biodegradability, low density, excellent biocompatibility and unique mechanics, spider silk has been used as a natural biomaterial for a myriad of applications. First clinical applications of spider silk as suture material go back to the 18th century. Nowadays, since n...
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Online Access: | https://www.mdpi.com/1420-3049/25/3/737 |
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doaj-f97c47f4f0b34204ad7eec8c09045dcc2020-11-25T02:03:34ZengMDPI AGMolecules1420-30492020-02-0125373710.3390/molecules25030737molecules25030737Spider Silk for Tissue Engineering ApplicationsSahar Salehi0Kim Koeck1Thomas Scheibel2Department for Biomaterials, University of Bayreuth, Prof.-Rüdiger-Bormann-Strasse 1, 95447 Bayreuth, GermanyDepartment for Biomaterials, University of Bayreuth, Prof.-Rüdiger-Bormann-Strasse 1, 95447 Bayreuth, GermanyDepartment for Biomaterials, University of Bayreuth, Prof.-Rüdiger-Bormann-Strasse 1, 95447 Bayreuth, GermanyDue to its properties, such as biodegradability, low density, excellent biocompatibility and unique mechanics, spider silk has been used as a natural biomaterial for a myriad of applications. First clinical applications of spider silk as suture material go back to the 18th century. Nowadays, since natural production using spiders is limited due to problems with farming spiders, recombinant production of spider silk proteins seems to be the best way to produce material in sufficient quantities. The availability of recombinantly produced spider silk proteins, as well as their good processability has opened the path towards modern biomedical applications. Here, we highlight the research on spider silk-based materials in the field of tissue engineering and summarize various two-dimensional (2D) and three-dimensional (3D) scaffolds made of spider silk. Finally, different applications of spider silk-based materials are reviewed in the field of tissue engineering in vitro and in vivo.https://www.mdpi.com/1420-3049/25/3/737tissue engineeringbiofabricationhydrogelscoatingsfibersrecombinant spider silk proteins |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sahar Salehi Kim Koeck Thomas Scheibel |
spellingShingle |
Sahar Salehi Kim Koeck Thomas Scheibel Spider Silk for Tissue Engineering Applications Molecules tissue engineering biofabrication hydrogels coatings fibers recombinant spider silk proteins |
author_facet |
Sahar Salehi Kim Koeck Thomas Scheibel |
author_sort |
Sahar Salehi |
title |
Spider Silk for Tissue Engineering Applications |
title_short |
Spider Silk for Tissue Engineering Applications |
title_full |
Spider Silk for Tissue Engineering Applications |
title_fullStr |
Spider Silk for Tissue Engineering Applications |
title_full_unstemmed |
Spider Silk for Tissue Engineering Applications |
title_sort |
spider silk for tissue engineering applications |
publisher |
MDPI AG |
series |
Molecules |
issn |
1420-3049 |
publishDate |
2020-02-01 |
description |
Due to its properties, such as biodegradability, low density, excellent biocompatibility and unique mechanics, spider silk has been used as a natural biomaterial for a myriad of applications. First clinical applications of spider silk as suture material go back to the 18th century. Nowadays, since natural production using spiders is limited due to problems with farming spiders, recombinant production of spider silk proteins seems to be the best way to produce material in sufficient quantities. The availability of recombinantly produced spider silk proteins, as well as their good processability has opened the path towards modern biomedical applications. Here, we highlight the research on spider silk-based materials in the field of tissue engineering and summarize various two-dimensional (2D) and three-dimensional (3D) scaffolds made of spider silk. Finally, different applications of spider silk-based materials are reviewed in the field of tissue engineering in vitro and in vivo. |
topic |
tissue engineering biofabrication hydrogels coatings fibers recombinant spider silk proteins |
url |
https://www.mdpi.com/1420-3049/25/3/737 |
work_keys_str_mv |
AT saharsalehi spidersilkfortissueengineeringapplications AT kimkoeck spidersilkfortissueengineeringapplications AT thomasscheibel spidersilkfortissueengineeringapplications |
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