Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery
Background: Haemophilia is a disease of genetic origin, which causes a defect in blood coagulation. Under normal conditions, in the case of leakage from the blood vessels, the blood forms a clot that reduces or blocks the bleeding. This process involves the activation of several plasma proteins in a...
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doaj-f97f636a3b00424580a95c4cd4d27a732020-11-25T00:52:52ZengMDPI AGInternational Journal of Environmental Research and Public Health1660-46012019-04-01168138610.3390/ijerph16081386ijerph16081386Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial SurgeryLuigi Laino0Marco Cicciù1Luca Fiorillo2Salvatore Crimi3Alberto Bianchi4Giulia Amoroso5Ines Paola Monte6Alan Scott Herford7Gabriele Cervino8Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania “Luigi Vanvitelli”, 80100 Napoli, ItalyDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina (ME), ItalyMultidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania “Luigi Vanvitelli”, 80100 Napoli, ItalyDepartment of Biomedical and Surgical and Biomedical Sciences Catania University, 95125 Catania (CT), ItalyDepartment of Biomedical and Surgical and Biomedical Sciences Catania University, 95125 Catania (CT), ItalyDepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina (ME), ItalyDepartment of General Surgery and Medical-Surgery Specialties, University of Catania, 95125 Catania (CT), ItalyDepartment of Maxillofacial Surgery, Loma Linda University, Loma Linda, CA 92350, USADepartment of Biomedical and Dental Sciences and Morphological and Functional Imaging, Messina University, 98100 Messina (ME), ItalyBackground: Haemophilia is a disease of genetic origin, which causes a defect in blood coagulation. Under normal conditions, in the case of leakage from the blood vessels, the blood forms a clot that reduces or blocks the bleeding. This process involves the activation of several plasma proteins in a cascade-like species. Two of these proteins, produced in the liver, factor VIII and factor IX, are deficient or present a functional defect in people with haemophilia. Because of this deficit, the haemophiliacs easily suffer external and internal bleeding. Surgical treatment of these patients is to be observed, and often their treatment is delayed due to unclear guidelines and risks in treating these patients. The aim is to provide clear guidelines in the case of surgical treatment of these patients. Methods: In this study, we have considered all the guidelines that refer to the gold-maxillofacial surgery, focusing on the literature of the last 10 years. Results: Surely, this collection of guidelines will favor the choice of the clinician towards safer and predictable protocols. This study does not want to create a guideline but evaluates the literature of the last 10 years, and highlights the latest for the treatment of these patients., with the aim of informing the pathology and at the same time making the surgical maneuvers safer. Conclusions: Despite the research of literature has produced few results, it was nevertheless possible to draw up a guideline thanks to additional information extrapolated from textbooks and other scientific articles. According to the guidelines, it is possible to proceed to the treatment of these patients, if with appropriate therapy in a safe and risk-free manner.https://www.mdpi.com/1660-4601/16/8/1386haemophiliasurgerymaxillo-facialoralcoagulopathiesguidelines |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Luigi Laino Marco Cicciù Luca Fiorillo Salvatore Crimi Alberto Bianchi Giulia Amoroso Ines Paola Monte Alan Scott Herford Gabriele Cervino |
spellingShingle |
Luigi Laino Marco Cicciù Luca Fiorillo Salvatore Crimi Alberto Bianchi Giulia Amoroso Ines Paola Monte Alan Scott Herford Gabriele Cervino Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery International Journal of Environmental Research and Public Health haemophilia surgery maxillo-facial oral coagulopathies guidelines |
author_facet |
Luigi Laino Marco Cicciù Luca Fiorillo Salvatore Crimi Alberto Bianchi Giulia Amoroso Ines Paola Monte Alan Scott Herford Gabriele Cervino |
author_sort |
Luigi Laino |
title |
Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery |
title_short |
Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery |
title_full |
Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery |
title_fullStr |
Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery |
title_full_unstemmed |
Surgical Risk on Patients with Coagulopathies: Guidelines on Hemophiliac Patients for Oro-Maxillofacial Surgery |
title_sort |
surgical risk on patients with coagulopathies: guidelines on hemophiliac patients for oro-maxillofacial surgery |
publisher |
MDPI AG |
series |
International Journal of Environmental Research and Public Health |
issn |
1660-4601 |
publishDate |
2019-04-01 |
description |
Background: Haemophilia is a disease of genetic origin, which causes a defect in blood coagulation. Under normal conditions, in the case of leakage from the blood vessels, the blood forms a clot that reduces or blocks the bleeding. This process involves the activation of several plasma proteins in a cascade-like species. Two of these proteins, produced in the liver, factor VIII and factor IX, are deficient or present a functional defect in people with haemophilia. Because of this deficit, the haemophiliacs easily suffer external and internal bleeding. Surgical treatment of these patients is to be observed, and often their treatment is delayed due to unclear guidelines and risks in treating these patients. The aim is to provide clear guidelines in the case of surgical treatment of these patients. Methods: In this study, we have considered all the guidelines that refer to the gold-maxillofacial surgery, focusing on the literature of the last 10 years. Results: Surely, this collection of guidelines will favor the choice of the clinician towards safer and predictable protocols. This study does not want to create a guideline but evaluates the literature of the last 10 years, and highlights the latest for the treatment of these patients., with the aim of informing the pathology and at the same time making the surgical maneuvers safer. Conclusions: Despite the research of literature has produced few results, it was nevertheless possible to draw up a guideline thanks to additional information extrapolated from textbooks and other scientific articles. According to the guidelines, it is possible to proceed to the treatment of these patients, if with appropriate therapy in a safe and risk-free manner. |
topic |
haemophilia surgery maxillo-facial oral coagulopathies guidelines |
url |
https://www.mdpi.com/1660-4601/16/8/1386 |
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