Moderate Continuous Aerobic Exercise Training Improves Cardiomyocyte Contractility in Β1 Adrenergic Receptor Knockout Mice

Moderate Continuous Aerobic Exercise Training Improves Cardiomyocyte Contractility in Β1 Adrenergic Receptor Knockout Mice

Abstract Background: The lack of cardiac β1-adrenergic receptors (β1-AR) negatively affects the regulation of both cardiac inotropy and lusitropy, leading, in the long term, to heart failure (HF). Moderate-intensity aerobic exercise (MCAE) is recommended as an adjunctive therapy for patients with H...

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Bibliographic Details
Main Authors: Aurora Corrêa Rodrigues, Antônio José Natali, Daise Nunes Queiroz da Cunha, Alexandre Jayme Lopes Dantas Costa, Anselmo Gomes de Moura, Miguel Araújo Carneiro-Júnior, Leonardo Bonato Félix, Patrícia Chakur Brum, Thales Nicolau Prímola-Gomes
Format: Article
Language:English
Published: Sociedade Brasileira de Cardiologia (SBC) 2018-02-01
Series:Arquivos Brasileiros de Cardiologia
Subjects:
Insuficiência Cardíaca
Exercício
Contração Miocárdica
Miócitos Cardíacos
Antagonistas de Receptores Adrenérgicos beta 1
Camundongos
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018005002107&lng=en&tlng=en

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