Seizure (Ictal)—EEG Characteristics in Subgroups of Depressive Disorder in Patients Receiving Electroconvulsive Therapy (ECT)—A Preliminary Study and Multivariate Approach
Objectives. Examine frequency distributions of ictal EEG after ECT stimulation in diagnostic subgroups of depression. Methods. EEG registration was consecutively monitored in 33 patients after ECT stimulation. Patients were diagnosed according to DSM IV and subdivided into: (1) major depressive diso...
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doaj-f98f7576aec34dfb806f2533158c05e42020-11-24T21:06:08ZengHindawi LimitedComputational Intelligence and Neuroscience1687-52651687-52732009-01-01200910.1155/2009/965209965209Seizure (Ictal)—EEG Characteristics in Subgroups of Depressive Disorder in Patients Receiving Electroconvulsive Therapy (ECT)—A Preliminary Study and Multivariate ApproachBjörn Wahlund0Paolo Piazza1Dietrich von Rosen2Benny Liberg3Hans Liljenström4Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, SwedenDepartment of Energy and Engineering, Swedish University of Agricultural Sciences, 750 07 Uppsala, SwedenDepartment of Energy and Engineering, Swedish University of Agricultural Sciences, 750 07 Uppsala, SwedenDepartment of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Karolinska University Hospital, Huddinge, 141 86 Stockholm, SwedenDepartment of Energy and Engineering, Swedish University of Agricultural Sciences, 750 07 Uppsala, SwedenObjectives. Examine frequency distributions of ictal EEG after ECT stimulation in diagnostic subgroups of depression. Methods. EEG registration was consecutively monitored in 33 patients after ECT stimulation. Patients were diagnosed according to DSM IV and subdivided into: (1) major depressive disorder with psychotic features (n=7), (2) unipolar depression (n=20), and (3) bipolar depression (n=6). Results. Results indicate that the diagnostically subgroups differ in their ictal EEG frequency spectrumml: (1) psychotic depression has a high occurrence of delta and theta waves, (2) unipolar depression has high occurrence of delta, theta and gamma waves, and (3) bipolar depression has a high occurrence of gamma waves. A linear discriminant function separated the three clinical groups with an accuracy of 94%. Conclusion. Psychotic depressed patients differ from bipolar depression in their frequency based on probability distribution of ictal EEG. Psychotic depressed patients show more prominent slowing of EEG than nonpsychotic depressed patients. Thus the EEG results may be supportive in classifying subgroups of depression already at the start of the ECT treatment.http://dx.doi.org/10.1155/2009/965209 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Björn Wahlund Paolo Piazza Dietrich von Rosen Benny Liberg Hans Liljenström |
spellingShingle |
Björn Wahlund Paolo Piazza Dietrich von Rosen Benny Liberg Hans Liljenström Seizure (Ictal)—EEG Characteristics in Subgroups of Depressive Disorder in Patients Receiving Electroconvulsive Therapy (ECT)—A Preliminary Study and Multivariate Approach Computational Intelligence and Neuroscience |
author_facet |
Björn Wahlund Paolo Piazza Dietrich von Rosen Benny Liberg Hans Liljenström |
author_sort |
Björn Wahlund |
title |
Seizure (Ictal)—EEG Characteristics in Subgroups of Depressive Disorder in Patients Receiving Electroconvulsive Therapy (ECT)—A Preliminary Study and Multivariate Approach |
title_short |
Seizure (Ictal)—EEG Characteristics in Subgroups of Depressive Disorder in Patients Receiving Electroconvulsive Therapy (ECT)—A Preliminary Study and Multivariate Approach |
title_full |
Seizure (Ictal)—EEG Characteristics in Subgroups of Depressive Disorder in Patients Receiving Electroconvulsive Therapy (ECT)—A Preliminary Study and Multivariate Approach |
title_fullStr |
Seizure (Ictal)—EEG Characteristics in Subgroups of Depressive Disorder in Patients Receiving Electroconvulsive Therapy (ECT)—A Preliminary Study and Multivariate Approach |
title_full_unstemmed |
Seizure (Ictal)—EEG Characteristics in Subgroups of Depressive Disorder in Patients Receiving Electroconvulsive Therapy (ECT)—A Preliminary Study and Multivariate Approach |
title_sort |
seizure (ictal)—eeg characteristics in subgroups of depressive disorder in patients receiving electroconvulsive therapy (ect)—a preliminary study and multivariate approach |
publisher |
Hindawi Limited |
series |
Computational Intelligence and Neuroscience |
issn |
1687-5265 1687-5273 |
publishDate |
2009-01-01 |
description |
Objectives. Examine frequency distributions of ictal EEG after ECT stimulation in diagnostic subgroups of depression. Methods. EEG registration was consecutively monitored in 33 patients after ECT stimulation. Patients were diagnosed according to DSM IV and subdivided into: (1) major depressive disorder with psychotic features (n=7), (2) unipolar depression (n=20), and (3) bipolar depression (n=6). Results. Results indicate that the diagnostically subgroups differ in their ictal EEG frequency spectrumml: (1) psychotic depression has a high occurrence of delta and theta waves, (2) unipolar depression has high occurrence of delta, theta and gamma waves, and (3) bipolar depression has a high occurrence of gamma waves. A linear discriminant function separated the three clinical groups with an accuracy of 94%. Conclusion. Psychotic depressed patients differ from bipolar depression in their frequency based on probability distribution of ictal EEG. Psychotic depressed patients show more prominent slowing of EEG than nonpsychotic depressed patients. Thus the EEG results may be supportive in classifying subgroups of depression already at the start of the ECT treatment. |
url |
http://dx.doi.org/10.1155/2009/965209 |
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