Current Insights on Early Life Nutrition and Prevention of Allergy
The incidence of allergic diseases in childhood appears to have significantly increased over the last decades. Since environmental factors, including diet, have been thought to play a significant role in the development of these diseases, there is great interest in identifying prevention strategies...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-08-01
|
Series: | Frontiers in Pediatrics |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fped.2020.00448/full |
id |
doaj-f9b83d41b191445b8166b067962c8e17 |
---|---|
record_format |
Article |
spelling |
doaj-f9b83d41b191445b8166b067962c8e172020-11-25T02:59:35ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602020-08-01810.3389/fped.2020.00448554646Current Insights on Early Life Nutrition and Prevention of AllergyGiuliana FerranteMaurizio CartaClaudio MontanteVeronica NotarbartoloGiovanni CorselloMario GiuffrèThe incidence of allergic diseases in childhood appears to have significantly increased over the last decades. Since environmental factors, including diet, have been thought to play a significant role in the development of these diseases, there is great interest in identifying prevention strategies related to early nutritional interventions. Breastfeeding is critical for the immune development of newborns and infants through immune-modulating properties and it impacts the establishment of a healthy gut microbiota. However, the evidence for a protective role of breastfeeding against the development of food allergy in childhood is controversial, and there is little evidence to support the benefits of an antigen avoidance diet during lactation. Although it is not possible to draw a definitive conclusion about the protective role of breast milk against allergic diseases, exclusive breastfeeding is still recommended throughout the first 6 months of life due to associated health benefits. Furthermore, recommendations regarding complementary feeding in infancy have been significantly modified over the last few decades. Several studies have shown that delayed exposure to allergenic foods does not have a role in allergy prevention and recent guidelines recommend against delaying the introduction of complementary foods after 6 months of age, both in high- and low-risk infants. However, trials investigating this dietary approach have reported equivocal results so far. This review summarizes the available high-quality evidence regarding the efficacy of the principal dietary interventions proposed in early life to prevent allergic diseases in children.https://www.frontiersin.org/article/10.3389/fped.2020.00448/fullnutritionallergypreventionbreastfeedingmicrobiotadiet |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Giuliana Ferrante Maurizio Carta Claudio Montante Veronica Notarbartolo Giovanni Corsello Mario Giuffrè |
spellingShingle |
Giuliana Ferrante Maurizio Carta Claudio Montante Veronica Notarbartolo Giovanni Corsello Mario Giuffrè Current Insights on Early Life Nutrition and Prevention of Allergy Frontiers in Pediatrics nutrition allergy prevention breastfeeding microbiota diet |
author_facet |
Giuliana Ferrante Maurizio Carta Claudio Montante Veronica Notarbartolo Giovanni Corsello Mario Giuffrè |
author_sort |
Giuliana Ferrante |
title |
Current Insights on Early Life Nutrition and Prevention of Allergy |
title_short |
Current Insights on Early Life Nutrition and Prevention of Allergy |
title_full |
Current Insights on Early Life Nutrition and Prevention of Allergy |
title_fullStr |
Current Insights on Early Life Nutrition and Prevention of Allergy |
title_full_unstemmed |
Current Insights on Early Life Nutrition and Prevention of Allergy |
title_sort |
current insights on early life nutrition and prevention of allergy |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Pediatrics |
issn |
2296-2360 |
publishDate |
2020-08-01 |
description |
The incidence of allergic diseases in childhood appears to have significantly increased over the last decades. Since environmental factors, including diet, have been thought to play a significant role in the development of these diseases, there is great interest in identifying prevention strategies related to early nutritional interventions. Breastfeeding is critical for the immune development of newborns and infants through immune-modulating properties and it impacts the establishment of a healthy gut microbiota. However, the evidence for a protective role of breastfeeding against the development of food allergy in childhood is controversial, and there is little evidence to support the benefits of an antigen avoidance diet during lactation. Although it is not possible to draw a definitive conclusion about the protective role of breast milk against allergic diseases, exclusive breastfeeding is still recommended throughout the first 6 months of life due to associated health benefits. Furthermore, recommendations regarding complementary feeding in infancy have been significantly modified over the last few decades. Several studies have shown that delayed exposure to allergenic foods does not have a role in allergy prevention and recent guidelines recommend against delaying the introduction of complementary foods after 6 months of age, both in high- and low-risk infants. However, trials investigating this dietary approach have reported equivocal results so far. This review summarizes the available high-quality evidence regarding the efficacy of the principal dietary interventions proposed in early life to prevent allergic diseases in children. |
topic |
nutrition allergy prevention breastfeeding microbiota diet |
url |
https://www.frontiersin.org/article/10.3389/fped.2020.00448/full |
work_keys_str_mv |
AT giulianaferrante currentinsightsonearlylifenutritionandpreventionofallergy AT mauriziocarta currentinsightsonearlylifenutritionandpreventionofallergy AT claudiomontante currentinsightsonearlylifenutritionandpreventionofallergy AT veronicanotarbartolo currentinsightsonearlylifenutritionandpreventionofallergy AT giovannicorsello currentinsightsonearlylifenutritionandpreventionofallergy AT mariogiuffre currentinsightsonearlylifenutritionandpreventionofallergy |
_version_ |
1724701451324751872 |