Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice
Background: Statins are recommended for cardiovascular protection for people with diabetes (high-risk groups). This study aimed to evaluate the gap between the guidelines of statin utilization and clinical practice among outpatients with type 2 diabetes regarding the patient's age and gender, t...
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doaj-f9bf233d489443b98fc43f2bc8f18ef72020-11-25T01:06:34ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362019-01-01241151510.4103/jrms.JRMS_100_18Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practiceMohamed Anwar HammadSyed Azhar Syed SulaimanNor Azizah AzizDzul Azri Mohamed NoorBackground: Statins are recommended for cardiovascular protection for people with diabetes (high-risk groups). This study aimed to evaluate the gap between the guidelines of statin utilization and clinical practice among outpatients with type 2 diabetes regarding the patient's age and gender, to assess if this preventive drug is being satisfactorily utilized or not. Materials and Methods: In this cross-sectional study, patients aged <40 or >75 years, pregnant patients, and patients with type 1 diabetes, human immunodeficiency virus, or liver cirrhosis were excluded. Demographics, laboratory parameters, and prevalence of exposure to statin therapy were evaluated. This study was guided by the 2013 American College of Cardiology/American Heart Association cholesterol guidelines. IBM SPSS software was used for data management. Results: The study cohort involved 576 patients, with age being 58.3 ± 8.9 years. There were 50.5% of females and 49.5% of males. Overall 81.1% of patients aged 58.8 ± 8.8 years were statin users and 18.9% of patients aged 56.2 ± 9 years were statin nonusers. About 83.2% of females and 78.9% of males were prescribed statins. Statin medications included simvastatin 79.2%, atorvastatin 11.6%, lovastatin 5.8%, rosuvastatin 2.1%, and pravastatin 1.3%. Statin users' and nonusers' adherence was 56.5%, and 41.3% (P = 0.004), respectively. The adherence to medication plan of females and males was 55.7% and 51.6%, respectively (P = 0.004). Conclusion: Patients with diabetes who are at high risk of cardiovascular events, exposure to statin treatment is significantly less than perfect position both in females and males. Nearly one-fifth of the patients with type 2 diabetes are not using statins despite therapeutic necessities.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2019;volume=24;issue=1;spage=15;epage=15;aulast=Hammadageclinical gapgendermalaysiapractice guidelinesstatin medicationtype 2 diabetes |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohamed Anwar Hammad Syed Azhar Syed Sulaiman Nor Azizah Aziz Dzul Azri Mohamed Noor |
spellingShingle |
Mohamed Anwar Hammad Syed Azhar Syed Sulaiman Nor Azizah Aziz Dzul Azri Mohamed Noor Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice Journal of Research in Medical Sciences age clinical gap gender malaysia practice guidelines statin medication type 2 diabetes |
author_facet |
Mohamed Anwar Hammad Syed Azhar Syed Sulaiman Nor Azizah Aziz Dzul Azri Mohamed Noor |
author_sort |
Mohamed Anwar Hammad |
title |
Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice |
title_short |
Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice |
title_full |
Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice |
title_fullStr |
Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice |
title_full_unstemmed |
Prescribing statins among patients with type 2 diabetes: The clinical gap between the guidelines and practice |
title_sort |
prescribing statins among patients with type 2 diabetes: the clinical gap between the guidelines and practice |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Research in Medical Sciences |
issn |
1735-1995 1735-7136 |
publishDate |
2019-01-01 |
description |
Background: Statins are recommended for cardiovascular protection for people with diabetes (high-risk groups). This study aimed to evaluate the gap between the guidelines of statin utilization and clinical practice among outpatients with type 2 diabetes regarding the patient's age and gender, to assess if this preventive drug is being satisfactorily utilized or not. Materials and Methods: In this cross-sectional study, patients aged <40 or >75 years, pregnant patients, and patients with type 1 diabetes, human immunodeficiency virus, or liver cirrhosis were excluded. Demographics, laboratory parameters, and prevalence of exposure to statin therapy were evaluated. This study was guided by the 2013 American College of Cardiology/American Heart Association cholesterol guidelines. IBM SPSS software was used for data management. Results: The study cohort involved 576 patients, with age being 58.3 ± 8.9 years. There were 50.5% of females and 49.5% of males. Overall 81.1% of patients aged 58.8 ± 8.8 years were statin users and 18.9% of patients aged 56.2 ± 9 years were statin nonusers. About 83.2% of females and 78.9% of males were prescribed statins. Statin medications included simvastatin 79.2%, atorvastatin 11.6%, lovastatin 5.8%, rosuvastatin 2.1%, and pravastatin 1.3%. Statin users' and nonusers' adherence was 56.5%, and 41.3% (P = 0.004), respectively. The adherence to medication plan of females and males was 55.7% and 51.6%, respectively (P = 0.004). Conclusion: Patients with diabetes who are at high risk of cardiovascular events, exposure to statin treatment is significantly less than perfect position both in females and males. Nearly one-fifth of the patients with type 2 diabetes are not using statins despite therapeutic necessities. |
topic |
age clinical gap gender malaysia practice guidelines statin medication type 2 diabetes |
url |
http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2019;volume=24;issue=1;spage=15;epage=15;aulast=Hammad |
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