Uncontrolled Confounders May Lead to False or Overvalued Radiomics Signature: A Proof of Concept Using Survival Analysis in a Multicenter Cohort of Kidney Cancer
PurposeWe aimed to explore potential confounders of prognostic radiomics signature predicting survival outcomes in clear cell renal cell carcinoma (ccRCC) patients and demonstrate how to control for them.Materials and MethodsPreoperative contrast enhanced abdominal CT scan of ccRCC patients along wi...
Main Authors: | Lin Lu, Firas S. Ahmed, Oguz Akin, Lyndon Luk, Xiaotao Guo, Hao Yang, Jin Yoon, A. Aari Hakimi, Lawrence H. Schwartz, Binsheng Zhao |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-05-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2021.638185/full |
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