Serum Amyloid Beta42 Is Not Eliminated by the Cirrhotic Liver: A Pilot Study

Serum Amyloid Beta42 Is Not Eliminated by the Cirrhotic Liver: A Pilot Study

Amyloid-beta (Aβ) deposition in the brain is the main pathological hallmark of Alzheimer disease. Peripheral clearance of Aβ may possibly also lower brain levels. Recent evidence suggested that hepatic clearance of Aβ42 is impaired in liver cirrhosis. To further test this hypothesis, serum Aβ42 was...

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Bibliographic Details
Main Authors: Reiner Wiest, Thomas S. Weiss, Lusine Danielyan, Christa Buechler
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Clinical Medicine
Subjects:
portal vein
MELD score
bilirubin
ascites
hepatic clearance
liver cirrhosis
Online Access:https://www.mdpi.com/2077-0383/10/12/2669

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