Identification of human glycosyltransferase genes expressed in erythroid cells predicts potential carbohydrate blood group loci

Abstract Glycans are biologically important structures synthesised by glycosyltransferase (GT) enzymes. Disruptive genetic null variants in GT genes can lead to serious illness but benign phenotypes are also seen, including antigenic differences on the red blood cell (RBC) surface, giving rise to bl...

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Bibliographic Details
Main Authors: Magnus Jöud, Mattias Möller, Martin L. Olsson
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-24445-5