Recommendations for the use of Japanese encephalitis vaccines

Japanese encephalitis (JE) is a mosquito-borne viral infection which is prevalent in Taiwan. The virus circulates in an enzootic cycle in pigs which serve as amplifying hosts. Outbreaks typically occur during summer. A universal vaccination program using 4-shot mouse brain-derived inactivated vaccin...

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Main Authors: Ping-Ing Lee, Yhu-Chering Huang, Kao-Pin Hwang, Ching-Chuan Liu, Cheng-Hsun Chiu, Po-Yen Chen, Chun-Yi Lu, Chih-Jung Chen, Luan-Yin Chang, Nan-Chang Chiu, Hsin Chi, Hsiao-Chuan Lin, Keh-Gong Wu, Yu-Huai Ho, Wu Sun, Tzou-Yien Lin
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Pediatrics and Neonatology
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957219305492
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spelling doaj-fa3916b0cb7f45bba6bfde142b322a252020-11-24T22:00:37ZengElsevierPediatrics and Neonatology1875-95722020-02-0161138Recommendations for the use of Japanese encephalitis vaccinesPing-Ing Lee0Yhu-Chering Huang1Kao-Pin Hwang2Ching-Chuan Liu3Cheng-Hsun Chiu4Po-Yen Chen5Chun-Yi Lu6Chih-Jung Chen7Luan-Yin Chang8Nan-Chang Chiu9Hsin Chi10Hsiao-Chuan Lin11Keh-Gong Wu12Yu-Huai Ho13Wu Sun14Tzou-Yien Lin15Department of Pediatrics, National Taiwan University Children's Hospital, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, Taiwan; Corresponding author. Department of Pediatrics, National Taiwan University Children's Hospital, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, No.8, Chung Shan S. Rd., Taipei, 10041, Taiwan. Tel.: +886 2 2312 3456 Ext.71515, fax: +886 2 2314 7450.Division of Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, TaiwanSchool of Medicine, China Medical University; Division of Pediatric Infectious Diseases, China Medical University Children's Hospital, TaiwanDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, TaiwanDivision of Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, TaiwanSection of Pediatric Infectious Diseases, Department of Pediatrics, Taichung Veterans General Hospital, TaiwanDepartment of Pediatrics, National Taiwan University Children's Hospital, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, TaiwanDivision of Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, TaiwanDepartment of Pediatrics, National Taiwan University Children's Hospital, National Taiwan University Hospital and National Taiwan University College of Medicine, National Taiwan University, TaiwanDepartment of Pediatrics, MacKay Children's Hospital, TaiwanDepartment of Pediatrics, MacKay Children's Hospital, TaiwanSchool of Medicine, China Medical University; Division of Pediatric Infectious Diseases, China Medical University Children's Hospital, TaiwanDepartment of Pediatrics, Taipei Veterans General Hospital and National Yang-Ming University, TaiwanDivision of Infection Diseases, Department of Internal Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, TaiwanPao-Chien Hospital, TaiwanDivision of Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, TaiwanJapanese encephalitis (JE) is a mosquito-borne viral infection which is prevalent in Taiwan. The virus circulates in an enzootic cycle in pigs which serve as amplifying hosts. Outbreaks typically occur during summer. A universal vaccination program using 4-shot mouse brain-derived inactivated vaccine has successfully controlled JE epidemics in Taiwan since 1968. More than 90% of JE cases in recent years were older than 20 years in Taiwan. Because of several drawbacks, mouse brain-derived vaccine has been replaced by newer generation JE vaccines, including inactivated Vero cell-derived vaccine and live chimeric vaccine. The present article describes the recommendations in Taiwan for the use of new JE vaccines and the schedules for shifting between different JE vaccines. Key Words: epidemiology, immunization schedule, Japanese encephalitis, vaccinationhttp://www.sciencedirect.com/science/article/pii/S1875957219305492
collection DOAJ
language English
format Article
sources DOAJ
author Ping-Ing Lee
Yhu-Chering Huang
Kao-Pin Hwang
Ching-Chuan Liu
Cheng-Hsun Chiu
Po-Yen Chen
Chun-Yi Lu
Chih-Jung Chen
Luan-Yin Chang
Nan-Chang Chiu
Hsin Chi
Hsiao-Chuan Lin
Keh-Gong Wu
Yu-Huai Ho
Wu Sun
Tzou-Yien Lin
spellingShingle Ping-Ing Lee
Yhu-Chering Huang
Kao-Pin Hwang
Ching-Chuan Liu
Cheng-Hsun Chiu
Po-Yen Chen
Chun-Yi Lu
Chih-Jung Chen
Luan-Yin Chang
Nan-Chang Chiu
Hsin Chi
Hsiao-Chuan Lin
Keh-Gong Wu
Yu-Huai Ho
Wu Sun
Tzou-Yien Lin
Recommendations for the use of Japanese encephalitis vaccines
Pediatrics and Neonatology
author_facet Ping-Ing Lee
Yhu-Chering Huang
Kao-Pin Hwang
Ching-Chuan Liu
Cheng-Hsun Chiu
Po-Yen Chen
Chun-Yi Lu
Chih-Jung Chen
Luan-Yin Chang
Nan-Chang Chiu
Hsin Chi
Hsiao-Chuan Lin
Keh-Gong Wu
Yu-Huai Ho
Wu Sun
Tzou-Yien Lin
author_sort Ping-Ing Lee
title Recommendations for the use of Japanese encephalitis vaccines
title_short Recommendations for the use of Japanese encephalitis vaccines
title_full Recommendations for the use of Japanese encephalitis vaccines
title_fullStr Recommendations for the use of Japanese encephalitis vaccines
title_full_unstemmed Recommendations for the use of Japanese encephalitis vaccines
title_sort recommendations for the use of japanese encephalitis vaccines
publisher Elsevier
series Pediatrics and Neonatology
issn 1875-9572
publishDate 2020-02-01
description Japanese encephalitis (JE) is a mosquito-borne viral infection which is prevalent in Taiwan. The virus circulates in an enzootic cycle in pigs which serve as amplifying hosts. Outbreaks typically occur during summer. A universal vaccination program using 4-shot mouse brain-derived inactivated vaccine has successfully controlled JE epidemics in Taiwan since 1968. More than 90% of JE cases in recent years were older than 20 years in Taiwan. Because of several drawbacks, mouse brain-derived vaccine has been replaced by newer generation JE vaccines, including inactivated Vero cell-derived vaccine and live chimeric vaccine. The present article describes the recommendations in Taiwan for the use of new JE vaccines and the schedules for shifting between different JE vaccines. Key Words: epidemiology, immunization schedule, Japanese encephalitis, vaccination
url http://www.sciencedirect.com/science/article/pii/S1875957219305492
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