Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission

The spatiotemporal regulation of membrane scaffolds recruitment and coupling between membrane deformation and fission in endocytosis are unclear. Here the authors show that lipid conversion at endocytic pits recruits SNX9, which couples local membrane constriction to fission in endocytosis.

Bibliographic Details
Main Authors:	Johannes Schöneberg, Martin Lehmann, Alexander Ullrich, York Posor, Wen-Ting Lo, Gregor Lichtner, Jan Schmoranzer, Volker Haucke, Frank Noé
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-06-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms15873

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spelling	doaj-fa470d0995f64498b209d0b17a5941cb2021-05-11T07:16:31ZengNature Publishing GroupNature Communications2041-17232017-06-018111710.1038/ncomms15873Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fissionJohannes Schöneberg0Martin Lehmann1Alexander Ullrich2York Posor3Wen-Ting Lo4Gregor Lichtner5Jan Schmoranzer6Volker Haucke7Frank Noé8Department of Mathematics and Computer Science, Freie Universität BerlinLeibniz-Institut für Molekulare PharmakologieDepartment of Mathematics and Computer Science, Freie Universität BerlinLeibniz-Institut für Molekulare PharmakologieLeibniz-Institut für Molekulare PharmakologieDepartment of Mathematics and Computer Science, Freie Universität BerlinLeibniz-Institut für Molekulare PharmakologieLeibniz-Institut für Molekulare PharmakologieDepartment of Mathematics and Computer Science, Freie Universität BerlinThe spatiotemporal regulation of membrane scaffolds recruitment and coupling between membrane deformation and fission in endocytosis are unclear. Here the authors show that lipid conversion at endocytic pits recruits SNX9, which couples local membrane constriction to fission in endocytosis.https://doi.org/10.1038/ncomms15873
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Johannes Schöneberg Martin Lehmann Alexander Ullrich York Posor Wen-Ting Lo Gregor Lichtner Jan Schmoranzer Volker Haucke Frank Noé
spellingShingle	Johannes Schöneberg Martin Lehmann Alexander Ullrich York Posor Wen-Ting Lo Gregor Lichtner Jan Schmoranzer Volker Haucke Frank Noé Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission Nature Communications
author_facet	Johannes Schöneberg Martin Lehmann Alexander Ullrich York Posor Wen-Ting Lo Gregor Lichtner Jan Schmoranzer Volker Haucke Frank Noé
author_sort	Johannes Schöneberg
title	Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
title_short	Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
title_full	Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
title_fullStr	Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
title_full_unstemmed	Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
title_sort	lipid-mediated px-bar domain recruitment couples local membrane constriction to endocytic vesicle fission
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2017-06-01
description	The spatiotemporal regulation of membrane scaffolds recruitment and coupling between membrane deformation and fission in endocytosis are unclear. Here the authors show that lipid conversion at endocytic pits recruits SNX9, which couples local membrane constriction to fission in endocytosis.
url	https://doi.org/10.1038/ncomms15873
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Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission

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