Spinal changes of a newly isolated neuropeptide endomorphin-2 concomitant with vincristine-induced allodynia.
Chemotherapy-induced neuropathic pain (CNP) is the major dose-limiting factor in cancer chemotherapy. However, the neural mechanisms underlying CNP remain unclear. There is increasing evidence implicating the involvement of spinal endomorphin-2 (EM2) in neuropathic pain. In this study, we used a vin...
Main Authors: | Yang Yang, Yong-Gang Zhang, Guo-An Lin, He-Qiu Xie, Hai-Tao Pan, Ben-Qing Huang, Ji-Dong Liu, Hui Liu, Nan Zhang, Li Li, Jian-Hua Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3933549?pdf=render |
Similar Items
-
Opposite effects of neuropeptide FF on central antinociception induced by endomorphin-1 and endomorphin-2 in mice.
by: Zi-long Wang, et al.
Published: (2014-01-01) -
SUPRASPINAL ANTI-ALLODYNIA AND REWARDING EFFECT OF ENDOMORPHINS IN RATS
by: Chen CM, et al.
Published: (2002) -
Endomorphin-2 Decreases Excitatory Synaptic Transmission in the Spinal Ventral Horn of the Rat
by: Zhen-Yu Wu, et al.
Published: (2017-08-01) -
Decreased endomorphin-2 and opioidreceptor in the spinal cord are associated with painful diabetic neuropathy
by: Zhen-Zhen Kou, et al.
Published: (2016-09-01) -
Minocycline Prevents the Development of Mechanical Allodynia in Mouse Models of Vincristine-Induced Peripheral Neuropathy
by: H. Starobova, et al.
Published: (2019-06-01)