Directing curli polymerization with DNA origami nucleators
Curli are bacterial functional amyloids that have gained interest as self-assembling biomaterial for biotechnology applications. Here, the authors show that DNA origami decorated with CsgB nucleator proteins induced the site-specific nucleation and subsequent fibrillization of CsgA proteins.
Bibliographic Details
Main Authors: |
Xiuhai Mao,
Ke Li,
Mengmeng Liu,
Xinyu Wang,
Tianxin Zhao,
Bolin An,
Mengkui Cui,
Yingfeng Li,
Jiahua Pu,
Jiang Li,
Lihua Wang,
Timothy K. Lu,
Chunhai Fan,
Chao Zhong |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2019-03-01
|
Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-019-09369-6
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