Directing curli polymerization with DNA origami nucleators
Curli are bacterial functional amyloids that have gained interest as self-assembling biomaterial for biotechnology applications. Here, the authors show that DNA origami decorated with CsgB nucleator proteins induced the site-specific nucleation and subsequent fibrillization of CsgA proteins.
Main Authors: | Xiuhai Mao, Ke Li, Mengmeng Liu, Xinyu Wang, Tianxin Zhao, Bolin An, Mengkui Cui, Yingfeng Li, Jiahua Pu, Jiang Li, Lihua Wang, Timothy K. Lu, Chunhai Fan, Chao Zhong |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-09369-6 |
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