EML4-ALK Fusion Lung Cancer: A Rare Acquired Event

A recurrent gene fusion between EML4 and ALK in 6.7% of non-small cell lung cancers (NSCLCs) and NKX2-1 (TTF1, TITF1) high-level amplifications in 12% of adenocarcinomas of the lung were independently reported recently. Because the EML4-ALK fusion was only shown by a reverse transcription-polymeras...

Full description

Bibliographic Details
Main Authors:	Sven Perner, Patrick L Wagner, Francesca Demichelis, Rohit Mehra, Christopher J LaFargue, Benjamin J Moss, Stefanie Arbogast, Alex Soltermann, Walter Weder, Thomas J Giordano, David G Beer, David S Rickman, Arul M Chinnaiyan, Holger Moch, Mark A Rubin
Format:	Article
Language:	English
Published:	Elsevier 2008-03-01
Series:	Neoplasia: An International Journal for Oncology Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1476558608801261

Internet

http://www.sciencedirect.com/science/article/pii/S1476558608801261

EML4-ALK Fusion Lung Cancer: A Rare Acquired Event

Internet

Similar Items