Microarrays as Model Biosensor Platforms to Investigate the Structure and Affinity of Aptamers

Immobilization of nucleic acid aptamer recognition elements selected free in solution onto the surface of biosensor platforms has proven challenging. This study investigated the binding of multiple aptamer/target pairs immobilized on a commercially available microarray as a model system mimicking bi...

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Bibliographic Details
Main Authors: Jennifer A. Martin, Yaroslav Chushak, Jorge L. Chávez, Joshua A. Hagen, Nancy Kelley-Loughnane
Format: Article
Published: Hindawi Limited 2016-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.1155/2016/9718612

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