The regulatory impact of RNA-binding proteins on microRNA targeting
miRNAs are loaded into Argonaute protein and repress complementary mRNA targets. Here the authors show the unappreciated role of RNA binding proteins for efficient miRNA targeting and expand the current understanding of miRNA targeting.
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2021-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-25078-5 |
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doaj-fa80ba4bd3e24c5eae00608527853f852021-08-22T11:39:01ZengNature Publishing GroupNature Communications2041-17232021-08-0112111510.1038/s41467-021-25078-5The regulatory impact of RNA-binding proteins on microRNA targetingSukjun Kim0Soyoung Kim1Hee Ryung Chang2Doyeon Kim3Junehee Park4Narae Son5Joori Park6Minhyuk Yoon7Gwangung Chae8Young-Kook Kim9V. Narry Kim10Yoon Ki Kim11Jin-Wu Nam12Chanseok Shin13Daehyun Baek14School of Biological Sciences, Seoul National UniversityDepartment of Agricultural Biotechnology, Seoul National UniversitySchool of Biological Sciences, Seoul National UniversitySchool of Biological Sciences, Seoul National UniversitySchool of Biological Sciences, Seoul National UniversitySchool of Biological Sciences, Seoul National UniversityCreative Research Initiatives Center for Molecular Biology of Translation, Korea UniversityDepartment of Agricultural Biotechnology, Seoul National UniversityDepartment of Agricultural Biotechnology, Seoul National UniversityDepartment of Biochemistry, Chonnam National University Medical SchoolSchool of Biological Sciences, Seoul National UniversityCreative Research Initiatives Center for Molecular Biology of Translation, Korea UniversityDepartment of Life Science, College of Natural Sciences, Hanyang UniversityDepartment of Agricultural Biotechnology, Seoul National UniversitySchool of Biological Sciences, Seoul National UniversitymiRNAs are loaded into Argonaute protein and repress complementary mRNA targets. Here the authors show the unappreciated role of RNA binding proteins for efficient miRNA targeting and expand the current understanding of miRNA targeting.https://doi.org/10.1038/s41467-021-25078-5 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sukjun Kim Soyoung Kim Hee Ryung Chang Doyeon Kim Junehee Park Narae Son Joori Park Minhyuk Yoon Gwangung Chae Young-Kook Kim V. Narry Kim Yoon Ki Kim Jin-Wu Nam Chanseok Shin Daehyun Baek |
spellingShingle |
Sukjun Kim Soyoung Kim Hee Ryung Chang Doyeon Kim Junehee Park Narae Son Joori Park Minhyuk Yoon Gwangung Chae Young-Kook Kim V. Narry Kim Yoon Ki Kim Jin-Wu Nam Chanseok Shin Daehyun Baek The regulatory impact of RNA-binding proteins on microRNA targeting Nature Communications |
author_facet |
Sukjun Kim Soyoung Kim Hee Ryung Chang Doyeon Kim Junehee Park Narae Son Joori Park Minhyuk Yoon Gwangung Chae Young-Kook Kim V. Narry Kim Yoon Ki Kim Jin-Wu Nam Chanseok Shin Daehyun Baek |
author_sort |
Sukjun Kim |
title |
The regulatory impact of RNA-binding proteins on microRNA targeting |
title_short |
The regulatory impact of RNA-binding proteins on microRNA targeting |
title_full |
The regulatory impact of RNA-binding proteins on microRNA targeting |
title_fullStr |
The regulatory impact of RNA-binding proteins on microRNA targeting |
title_full_unstemmed |
The regulatory impact of RNA-binding proteins on microRNA targeting |
title_sort |
regulatory impact of rna-binding proteins on microrna targeting |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2021-08-01 |
description |
miRNAs are loaded into Argonaute protein and repress complementary mRNA targets. Here the authors show the unappreciated role of RNA binding proteins for efficient miRNA targeting and expand the current understanding of miRNA targeting. |
url |
https://doi.org/10.1038/s41467-021-25078-5 |
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