Production of Induced Secondary Metabolites by a Co-Culture of Sponge-Associated Actinomycetes, Actinokineospora sp. EG49 and Nocardiopsis sp. RV163

Two sponge-derived actinomycetes, Actinokineospora sp. EG49 and Nocardiopsis sp. RV163, were grown in co-culture and the presence of induced metabolites monitored by 1H NMR. Ten known compounds, including angucycline, diketopiperazine and β-carboline derivatives 1–10, were isolated from the EtOAc ex...

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Bibliographic Details
Main Authors: Yousef Dashti, Tanja Grkovic, Usama Ramadan Abdelmohsen, Ute Hentschel, Ronald J. Quinn
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/12/5/3046