GPR30 regulates the EGFR-Akt cascade and predicts lower survival in patients with ovarian cancer

GPR30 regulates the EGFR-Akt cascade and predicts lower survival in patients with ovarian cancer

<p>Abstract</p> <p>Objectives</p> <p>G protein-coupled receptor 30 (GPR30) is a 7-transmembrane estrogen receptor that functions alongside traditional estrogen receptors to regulate the cellular responses to estrogen. Recent studies suggest that GPR30 expression is asso...

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Bibliographic Details
Main Authors: Fujiwara Satoe, Terai Yoshito, Kawaguchi Hiroshi, Takai Masaaki, Yoo Saha, Tanaka Yoshimichi, Tanaka Tomohito, Tsunetoh Satoshi, Sasaki Hiroshi, Kanemura Masanori, Tanabe Akiko, Yamashita Yoshiki, Ohmichi Masahide
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Journal of Ovarian Research
Subjects:
G protein-coupled receptor 30
GPR30
7-transmembrane estrogen receptor
EGFR
Akt
ERα; Clear cell carcinomas
Prognostic factor
Online Access:http://www.ovarianresearch.com/content/5/1/35

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