Polymorphisms in the Mitochondrial Genome Are Associated With Bullous Pemphigoid in Germans

Polymorphisms in the Mitochondrial Genome Are Associated With Bullous Pemphigoid in Germans

Bullous pemphigoid (BP) is the most prevalent autoimmune skin blistering disease and is characterized by the generation of autoantibodies against the hemidesmosomal proteins BP180 (type XVII collagen) and BP230. Most intriguingly, BP is distinct from other autoimmune diseases because it predominantl...

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Main Authors: Juliane Russlies, Anke Fähnrich, Mareike Witte, Junping Yin, Sandrine Benoit, Regine Gläser, Claudia Günter, Rüdiger Eming, Jeanette Erdmann, Damian Gola, Yask Gupta, Maike Marleen Holtsche, Johannes S. Kern, Inke R. König, Dimitra Kiritsi, Wolfgang Lieb, Christian D. Sadik, Miklós Sárdy, Franziska Schauer, Nina van Beek, Anke Weidinger, Margitta Worm, Detlef Zillikens, Enno Schmidt, Hauke Busch, Saleh M. Ibrahim, Misa Hirose
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
mitochondrial DNA
mitochondrial haplogroup
polymorphisms
autoimmune skin diseases
bullous pemphigoid
mitochondrial function
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02200/full

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