A case report of appendix mucinous adenocarcinoma that recurred after additional surgery and a brief literature review

• Main Authors: Wei Chen, Jun-Wen Ye, Xiao-ping Tan, Xiang Peng, Yan Zhang, Jing-Lin Liang, Mei-Jin Huang
• Format: Article
• Language: English
• Published: BMC 2020-08-01
• Series: BMC Surgery
• Subjects: Colorectal cancer; Appendiceal mucinous adenocarcinoma; HIPEC; Recurrence
• Online Access: http://link.springer.com/article/10.1186/s12893-020-00842-4

Abstract Background The clinical incidence of appendiceal mucinous adenocarcinoma is low. Moreover, the case reports of postoperative relapse after surgery are rarely based on literature search results. Here, we report such a case spanning nearly 7 years and and review the relevant literature. Case presentation A 50-year-old female underwent additional surgery after appendectomy, and pathological examination confirmed mucinous adenocarcinoma. The patients underwent HIPEC (hyperthermic intraoperative chemotherapy) and adjuvant chemotherapy. Twenty-six months after the previous surgeries, another surgery, HIPEC, and adjuvant chemotherapy were performed again due to tumour recurrence. To date, the follow-up time is 43 months, and no recurrence or metastasis has been found. Conclusions Appendix mucinous adenocarcinoma has a poor prognosis and the diagnosis depends on pathological and immunohistochemical examinations. Its clinical manifestations are non-specific, and CRS + HIPEC should be used for treatment, which is safe and effective.