Molecular Structure, In Vitro Anticancer Study and Molecular Docking of New Phosphate Derivatives of Betulin

A series of 30-diethylphosphate derivatives of betulin were synthesized and evaluated for their in vitro cytotoxic activity against human cancer cell lines, such as amelanotic melanoma (C-32), glioblastoma (SNB-19), and two lines of breast cancer (T47D, MDA-MB-231). The molecular structure and activ...

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Bibliographic Details
Main Authors: Elwira Chrobak, Maria Jastrzębska, Ewa Bębenek, Monika Kadela-Tomanek, Krzysztof Marciniec, Małgorzata Latocha, Roman Wrzalik, Joachim Kusz, Stanisław Boryczka
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/3/737