A retrospective study of 2228 cases with eyelid tumors
AIM: To describe the histopathologic and clinical features of eyelid tumor cases from Tianjin Eye Hospital during 2002 to 2015. METHODS: In this retrospective study, a total of 2228 cases of eyelid tumors with pathologic diagnoses were enrolled. The eyelid tumors were classified into three groups a...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2018-11-01
|
Series: | International Journal of Ophthalmology |
Subjects: | |
Online Access: | http://www.ijo.cn/en_publish/2018/11/20181116.pdf |
id |
doaj-fb32bde8749844bcaf2fa43b46600c05 |
---|---|
record_format |
Article |
spelling |
doaj-fb32bde8749844bcaf2fa43b46600c052020-11-25T00:30:29ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982018-11-0111111835184110.18240/ijo.2018.11.16A retrospective study of 2228 cases with eyelid tumorsSha-Sha Yu0Yun Zhao1Hong Zhao2Jin-Yong Lin3Xin Tang4Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300020, ChinaTianjin Eye Hospital, Tianjin 300020, ChinaTianjin Eye Hospital, Tianjin 300020, ChinaTianjin Eye Hospital, Tianjin 300020, ChinaClinical College of Ophthalmology, Tianjin Medical University, Tianjin 300020, China; Tianjin Eye Hospital, Tianjin 300020, China; Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin 300020, China; Tianjin Eye Institute, Tianjin 300020, ChinaAIM: To describe the histopathologic and clinical features of eyelid tumor cases from Tianjin Eye Hospital during 2002 to 2015. METHODS: In this retrospective study, a total of 2228 cases of eyelid tumors with pathologic diagnoses were enrolled. The eyelid tumors were classified into three groups according to tumor origin: epidermal, adnexal and miscellaneous, including melanocytic, neural and vascular lesions. Inflammatory tumor-like lesions were excluded. The clinical characteristics of the eyelid tumors were analyzed, including age, gender and lesion location. RESULTS: Most eyelid tumors were epidermal in origin (1080, 48.5%), followed by miscellaneous (885, 39.7%) and adnexal tumors (263, 11.8%). Among all the tumors, 292 (13.1%) were malignant lesions, 1910 (85.7%) benign and 26 (1.1%) premalignant lesions. Most malignant tumors originated from epidermal cells (60.0%), followed by adnexal cells (34.6%). The most common malignant tumors were basal cell carcinomas (56.5%) followed by sebaceous carcinoma (34.6%), squamous cell carcinomas (3.8%) and lymphoma/plasmocytoma (1.7%). The benign and premalignant eyelid lesions mostly originated from epidermal cells (46.4%) followed by miscellaneous cell sources (45.2%), including melanocytic nevus (33.8%), seborrheic keratosis (13.7%), squamous cell papilloma (13.0%) and epidermal cysts (11.5%). CONCLUSION: Eyelid tumors are mostly epithelial in origin. Benign tumors are significantly more common than malignant tumors with an obvious female predominance, and the most frequent malignant tumor are basal cell carcinoma, sebaceous carcinoma and squamous cell carcinomas. The tumor clinical features varied among the different subtypes.http://www.ijo.cn/en_publish/2018/11/20181116.pdfeyelid tumorsbenign tumorsmalignant tumorbasal cell carcinomasebaceous carcinomasquamous cell carcinomamelanocytic nevus |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sha-Sha Yu Yun Zhao Hong Zhao Jin-Yong Lin Xin Tang |
spellingShingle |
Sha-Sha Yu Yun Zhao Hong Zhao Jin-Yong Lin Xin Tang A retrospective study of 2228 cases with eyelid tumors International Journal of Ophthalmology eyelid tumors benign tumors malignant tumor basal cell carcinoma sebaceous carcinoma squamous cell carcinoma melanocytic nevus |
author_facet |
Sha-Sha Yu Yun Zhao Hong Zhao Jin-Yong Lin Xin Tang |
author_sort |
Sha-Sha Yu |
title |
A retrospective study of 2228 cases with eyelid tumors |
title_short |
A retrospective study of 2228 cases with eyelid tumors |
title_full |
A retrospective study of 2228 cases with eyelid tumors |
title_fullStr |
A retrospective study of 2228 cases with eyelid tumors |
title_full_unstemmed |
A retrospective study of 2228 cases with eyelid tumors |
title_sort |
retrospective study of 2228 cases with eyelid tumors |
publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
series |
International Journal of Ophthalmology |
issn |
2222-3959 2227-4898 |
publishDate |
2018-11-01 |
description |
AIM: To describe the histopathologic and clinical features of eyelid tumor cases from Tianjin Eye Hospital during 2002 to 2015.
METHODS: In this retrospective study, a total of 2228 cases of eyelid tumors with pathologic diagnoses were enrolled. The eyelid tumors were classified into three groups according to tumor origin: epidermal, adnexal and miscellaneous, including melanocytic, neural and vascular lesions. Inflammatory tumor-like lesions were excluded. The clinical characteristics of the eyelid tumors were analyzed, including age, gender and lesion location.
RESULTS: Most eyelid tumors were epidermal in origin (1080, 48.5%), followed by miscellaneous (885, 39.7%) and adnexal tumors (263, 11.8%). Among all the tumors, 292 (13.1%) were malignant lesions, 1910 (85.7%) benign and 26 (1.1%) premalignant lesions. Most malignant tumors originated from epidermal cells (60.0%), followed by adnexal cells (34.6%). The most common malignant tumors were basal cell carcinomas (56.5%) followed by sebaceous carcinoma (34.6%), squamous cell carcinomas (3.8%) and lymphoma/plasmocytoma (1.7%). The benign and premalignant eyelid lesions mostly originated from epidermal cells (46.4%) followed by miscellaneous cell sources (45.2%), including melanocytic nevus (33.8%), seborrheic keratosis (13.7%), squamous cell papilloma (13.0%) and epidermal cysts (11.5%).
CONCLUSION: Eyelid tumors are mostly epithelial in origin. Benign tumors are significantly more common than malignant tumors with an obvious female predominance, and the most frequent malignant tumor are basal cell carcinoma, sebaceous carcinoma and squamous cell carcinomas. The tumor clinical features varied among the different subtypes. |
topic |
eyelid tumors benign tumors malignant tumor basal cell carcinoma sebaceous carcinoma squamous cell carcinoma melanocytic nevus |
url |
http://www.ijo.cn/en_publish/2018/11/20181116.pdf |
work_keys_str_mv |
AT shashayu aretrospectivestudyof2228caseswitheyelidtumors AT yunzhao aretrospectivestudyof2228caseswitheyelidtumors AT hongzhao aretrospectivestudyof2228caseswitheyelidtumors AT jinyonglin aretrospectivestudyof2228caseswitheyelidtumors AT xintang aretrospectivestudyof2228caseswitheyelidtumors AT shashayu retrospectivestudyof2228caseswitheyelidtumors AT yunzhao retrospectivestudyof2228caseswitheyelidtumors AT hongzhao retrospectivestudyof2228caseswitheyelidtumors AT jinyonglin retrospectivestudyof2228caseswitheyelidtumors AT xintang retrospectivestudyof2228caseswitheyelidtumors |
_version_ |
1725326343812415488 |