Liver receptor homolog 1 transcriptionally regulates human bile salt export pump expression*

Liver receptor homolog 1 transcriptionally regulates human bile salt export pump expression*

The metabolic conversion of cholesterol into bile acids in liver is initiated by the rate-limiting cholesterol 7α-hydroxylase (CYP7A1), whereas the bile salt export pump (BSEP) is responsible for the canalicular secretion of bile acids. Liver receptor homolog 1 (LRH-1) is a key transcriptional facto...

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Bibliographic Details
Main Authors:	Xiulong Song, Rajani Kaimal, Bingfang Yan, Ruitang Deng
Format:	Article
Language:	English
Published:	Elsevier 2008-05-01
Series:	Journal of Lipid Research
Subjects:	bile acids bile acid synthesis and elimination cholesterol cholesterol metabolism farnesoid X receptor small heterodimer partner
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520425842

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