Health Promoting Life-Style Behaviors and Systemic Inflammation in African American and Caucasian Women Prior to Chemotherapy for Breast Cancer
Background: Racial disparities in breast cancer outcomes persist, with differential adverse outcomes in African American women. Although research has examined possible genetic differences, there has been little research on potentially modifiable characteristics such as health promoting behaviors. Th...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2014-07-01
|
Series: | Health Promotion Perspectives |
Subjects: | |
Online Access: | http://journals.tbzmed.ac.ir/HPP/Manuscript/HPP-4-18.pdf |
id |
doaj-fb5244e034564459881c111b4a237ed3 |
---|---|
record_format |
Article |
spelling |
doaj-fb5244e034564459881c111b4a237ed32020-11-24T21:47:49ZengTabriz University of Medical SciencesHealth Promotion Perspectives2228-64972228-64972014-07-0141182610.5681/hpp.2014.003Health Promoting Life-Style Behaviors and Systemic Inflammation in African American and Caucasian Women Prior to Chemotherapy for Breast CancerDebra E Lyon0Lathika Mohanraj1Debra Lynch Kelly2RK Elswick Jr3College of Nursing, University of Florida, Gainesville, Florida 32610, USADepartment of Family and Community Health Nursing, Virginia Commonwealth University, Richmond, VA 23298–0567, USADepartment of Family and Community Health Nursing, Virginia Commonwealth University, Richmond, VA 23298–0567, USADepartment of Family and Community Health Nursing, Virginia Commonwealth University, Richmond, VA 23298–0567, USABackground: Racial disparities in breast cancer outcomes persist, with differential adverse outcomes in African American women. Although research has examined possible genetic differences, there has been little research on potentially modifiable characteristics such as health promoting behaviors. The purpose of this article is to describe the characteristics and to compare the differences by race in lifestyle factors and inflammatory biomarkers in African American and Caucasian women with breast cancer. Methods: This is a baseline descriptive analysis from an ongoing randomized controlled trial that includes 124 women diagnosed with early stage breast cancer prior to chemotherapy. Data sources included medical records, self-report questionnaires and a blood sample for measures of inflammation. The statistical analysis included descriptive statistics and ANOVA models to determine differences between the two groups. Results: Overall, both groups had low levels of health promoting behaviors. African Americans had a significantly higher body mass index. Caucasian women consumed more alcohol. Levels of C-reactive protein and MIP-1β were significantly higher in African Americans. Conclusion: Potentially modifiable factors such as nutrition, physical activity and levels of inflammation warrant further attention.http://journals.tbzmed.ac.ir/HPP/Manuscript/HPP-4-18.pdfBreast cancerBiomarkersLifestyleDisparitiesC-reactive protein |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Debra E Lyon Lathika Mohanraj Debra Lynch Kelly RK Elswick Jr |
spellingShingle |
Debra E Lyon Lathika Mohanraj Debra Lynch Kelly RK Elswick Jr Health Promoting Life-Style Behaviors and Systemic Inflammation in African American and Caucasian Women Prior to Chemotherapy for Breast Cancer Health Promotion Perspectives Breast cancer Biomarkers Lifestyle Disparities C-reactive protein |
author_facet |
Debra E Lyon Lathika Mohanraj Debra Lynch Kelly RK Elswick Jr |
author_sort |
Debra E Lyon |
title |
Health Promoting Life-Style Behaviors and Systemic Inflammation in African American and Caucasian Women Prior to Chemotherapy for Breast Cancer |
title_short |
Health Promoting Life-Style Behaviors and Systemic Inflammation in African American and Caucasian Women Prior to Chemotherapy for Breast Cancer |
title_full |
Health Promoting Life-Style Behaviors and Systemic Inflammation in African American and Caucasian Women Prior to Chemotherapy for Breast Cancer |
title_fullStr |
Health Promoting Life-Style Behaviors and Systemic Inflammation in African American and Caucasian Women Prior to Chemotherapy for Breast Cancer |
title_full_unstemmed |
Health Promoting Life-Style Behaviors and Systemic Inflammation in African American and Caucasian Women Prior to Chemotherapy for Breast Cancer |
title_sort |
health promoting life-style behaviors and systemic inflammation in african american and caucasian women prior to chemotherapy for breast cancer |
publisher |
Tabriz University of Medical Sciences |
series |
Health Promotion Perspectives |
issn |
2228-6497 2228-6497 |
publishDate |
2014-07-01 |
description |
Background: Racial disparities in breast cancer outcomes persist, with differential adverse outcomes in African American women. Although research has examined possible genetic differences, there has been little research on potentially modifiable characteristics such as health promoting behaviors. The purpose of this article is to describe the characteristics and to compare the differences by race in lifestyle factors and inflammatory biomarkers in African American and Caucasian women with breast cancer.
Methods: This is a baseline descriptive analysis from an ongoing randomized controlled trial that includes 124 women diagnosed with early stage breast cancer prior to chemotherapy. Data sources included medical records, self-report questionnaires and a blood sample for measures of inflammation. The statistical analysis included descriptive statistics and ANOVA models to determine differences between the two groups.
Results: Overall, both groups had low levels of health promoting behaviors. African Americans had a significantly higher body mass index. Caucasian women consumed more alcohol. Levels of C-reactive protein and MIP-1β were significantly higher in African Americans.
Conclusion: Potentially modifiable factors such as nutrition, physical activity and levels of inflammation warrant further attention. |
topic |
Breast cancer Biomarkers Lifestyle Disparities C-reactive protein |
url |
http://journals.tbzmed.ac.ir/HPP/Manuscript/HPP-4-18.pdf |
work_keys_str_mv |
AT debraelyon healthpromotinglifestylebehaviorsandsystemicinflammationinafricanamericanandcaucasianwomenpriortochemotherapyforbreastcancer AT lathikamohanraj healthpromotinglifestylebehaviorsandsystemicinflammationinafricanamericanandcaucasianwomenpriortochemotherapyforbreastcancer AT debralynchkelly healthpromotinglifestylebehaviorsandsystemicinflammationinafricanamericanandcaucasianwomenpriortochemotherapyforbreastcancer AT rkelswickjr healthpromotinglifestylebehaviorsandsystemicinflammationinafricanamericanandcaucasianwomenpriortochemotherapyforbreastcancer |
_version_ |
1725895362076475392 |