| Summary: | Fast medicine dispensing system (FMDS) as a kind of medical logistic robot can dispense many drugs for one prescription at the same time. To guarantee the sustainability of drug dispensation, it is required that FMDS replenish drugs rapidly. The traditional order picking model (OPM) is difficult to meet the demand of prompt replenishment. To solve the problems of prolonged refilling route and inefficiency of drugs replenishment, a mixed refilling model based on multiple steps traveling salesman problem model (MTSPM) and vehicle routing problem model (VRPM) is proposed, and it is deployed in two circumstances of FMDS, including temporary replenishment mode (TRM) and concentrate replenishment mode (CRM). It not only meted the demand under different circumstances of drug replenishment but also shortened the refilling route significantly. First, the new pick sets were generated. Then, the orders of pick sets were optimized and the new paths were achieved. When the number of pickings is varied no more than 20, experiment results declared that the refilling route is the shortest by utilizing MTSPM when working under the TRM condition. Comparing MTSPM with OPM, the rate of refilling route length decreased up to 32.18%. Under the CRM condition, the refilling route is the shortest by utilizing VRPM. Comparing VRPM with OPM, the rate of refilling route length decreased up to 58.32%. Comparing VRPM with MTSPM, the rate of refilling route length has dropped more than 43.26%.
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