Pharmacological validation of an inward-rectifier potassium (Kir) channel as an insecticide target in the yellow fever mosquito Aedes aegypti.
Mosquitoes are important disease vectors that transmit a wide variety of pathogens to humans, including those that cause malaria and dengue fever. Insecticides have traditionally been deployed to control populations of disease-causing mosquitoes, but the emergence of insecticide resistance has sever...
Main Authors: | Matthew F Rouhier, Rene Raphemot, Jerod S Denton, Peter M Piermarini |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4069099?pdf=render |
Similar Items
-
Of Mosquitoes and Men: Targeting Inward Rectifier Potassium (Kir) Channels for the Development of New Therapeutics and Insecticides
by: Raphemot, Rene
Published: (2014) -
Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels.
by: Rene Raphemot, et al.
Published: (2014-01-01) -
Pharmacological Inhibition of Inward Rectifier Potassium Channels Induces Lethality in Larval <i>Aedes aegypti</i>
by: Renata Rusconi Trigueros, et al.
Published: (2018-11-01) -
Discovery, characterization and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.X and Kir7.1
by: Jerod S Denton
Published: (2011-11-01) -
Eliciting renal failure in mosquitoes with a small-molecule inhibitor of inward-rectifying potassium channels.
by: Rene Raphemot, et al.
Published: (2013-01-01)