ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION
Objective: To assess adequacy of anticoagulation in Warfarin treated patients with atrial fibrillation Study Design: Prospective observational study. Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases, Rawalpindi, from Nov 2019 to Apr 2020....
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doaj-fbef6e22318f43909826da2352610f2b2021-09-08T15:07:10ZengThe Army PressPakistan Armed Forces Medical Journal0030-96482411-88422020-12-01704768771doi.org/10.51253/pafmj.v70iSuppl-4.60216021ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATIONAmer Rauf0Azmat Hayat1Noor Shah2Kumail Abbas3Waqas Khalid4Sayed Tanveer Abbas Gilani5Armed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanArmed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD)/National University of Medical Sciences (NUMS) Rawalpindi PakistanObjective: To assess adequacy of anticoagulation in Warfarin treated patients with atrial fibrillation Study Design: Prospective observational study. Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases, Rawalpindi, from Nov 2019 to Apr 2020. Methodology: All individuals fulfilling the inclusion criteria were enrolled in the study after their consent. Based upon their serial International Normalized Ratio (INR) values, Time in Therapeutic Range (TTR) was calculated using Rosendaal method. A TTR>70% was a marker of adequate anticoagulation. Factors associated with TTR <70% were identified. Results: Total 70 participants were included in the study. Mean age (± SD) was 51.43 (± 11.27) years. Thirty four (48.6%) were males and 36 (51.4%) were females. Twenty four (34.3%) had valvular atrial fibrillation while 46 (65.7%) had non-valvular atrial fibrillation. Overall, TTR>70% was observed in 29 (41.4%) of study participants. Poly-pharmacy and multiple co-morbidities were identified as statistically significant factors associated with subtherapeutic anticoagulation (TTR<70%). Conclusion: Determined TTR of study population indicates poor anticoagulation control in majority of patients being anticoagulated with Warfar in highlighting the need for focused interventions such as dedicated anticoagulation clinics and patient education.https://pafmj.org/index.php/PAFMJ/article/view/6021anticoagulantsatrial fibrillationwarfarin |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Amer Rauf Azmat Hayat Noor Shah Kumail Abbas Waqas Khalid Sayed Tanveer Abbas Gilani |
spellingShingle |
Amer Rauf Azmat Hayat Noor Shah Kumail Abbas Waqas Khalid Sayed Tanveer Abbas Gilani ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION Pakistan Armed Forces Medical Journal anticoagulants atrial fibrillation warfarin |
author_facet |
Amer Rauf Azmat Hayat Noor Shah Kumail Abbas Waqas Khalid Sayed Tanveer Abbas Gilani |
author_sort |
Amer Rauf |
title |
ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION |
title_short |
ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION |
title_full |
ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION |
title_fullStr |
ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION |
title_full_unstemmed |
ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION |
title_sort |
anticoagulation control among patients with atrial fibrillation |
publisher |
The Army Press |
series |
Pakistan Armed Forces Medical Journal |
issn |
0030-9648 2411-8842 |
publishDate |
2020-12-01 |
description |
Objective: To assess adequacy of anticoagulation in Warfarin treated patients with atrial fibrillation
Study Design: Prospective observational study.
Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases, Rawalpindi, from Nov 2019 to Apr 2020.
Methodology: All individuals fulfilling the inclusion criteria were enrolled in the study after their consent. Based upon their serial International Normalized Ratio (INR) values, Time in Therapeutic Range (TTR) was calculated using Rosendaal method. A TTR>70% was a marker of adequate anticoagulation. Factors associated with TTR <70% were identified.
Results: Total 70 participants were included in the study. Mean age (± SD) was 51.43 (± 11.27) years. Thirty four (48.6%) were males and 36 (51.4%) were females. Twenty four (34.3%) had valvular atrial fibrillation while 46 (65.7%) had non-valvular atrial fibrillation. Overall, TTR>70% was observed in 29 (41.4%) of study participants. Poly-pharmacy and multiple co-morbidities were identified as statistically significant factors associated with subtherapeutic anticoagulation (TTR<70%).
Conclusion: Determined TTR of study population indicates poor anticoagulation control in majority of patients being anticoagulated with Warfar in highlighting the need for focused interventions such as dedicated anticoagulation clinics and patient education. |
topic |
anticoagulants atrial fibrillation warfarin |
url |
https://pafmj.org/index.php/PAFMJ/article/view/6021 |
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