Enhanced Chemosensitivity by Targeting Nanog in Head and Neck Squamous Cell Carcinomas

Enhanced Chemosensitivity by Targeting Nanog in Head and Neck Squamous Cell Carcinomas

Chemo-resistance is the major cause of high mortality in head and neck squamous cell carcinomas (HNSCC) in which HNSCC-derived cancer stem cells (CSCs) may be involved. Previously, we enriched a subpopulation of HNSCC-derived spheroid cells (SC) (HNSCC-SC) and identified Nanog as a CSCs marker. The...

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Bibliographic Details
Main Authors: Chuan-En Huang, Cheng-Chia Yu, Fang-Wei Hu, Ming-Yung Chou, Lo-Lin Tsai
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:International Journal of Molecular Sciences
Subjects:
head and neck squamous cell carcinomas
Nanog
cancer stem cells
chemosensitivity
Online Access:http://www.mdpi.com/1422-0067/15/9/14935

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