A novel signal transduction pathway that modulates rhl quorum sensing and bacterial virulence in Pseudomonas aeruginosa.

The rhl quorum-sensing (QS) system plays critical roles in the pathogenesis of P. aeruginosa. However, the regulatory effects that occur directly upstream of the rhl QS system are poorly understood. Here, we show that deletion of gene encoding for the two-component sensor BfmS leads to the activatio...

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Bibliographic Details
Main Authors: Qiao Cao, Yue Wang, Feifei Chen, Yongjie Xia, Jingyu Lou, Xue Zhang, Nana Yang, Xiaoxu Sun, Qin Zhang, Chao Zhuo, Xi Huang, Xin Deng, Cai-Guang Yang, Yan Ye, Jing Zhao, Min Wu, Lefu Lan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4148453?pdf=render