Variable evidence on metformin efficiency as weight-reducing and antiblastomogenic agent: causes and consequences

The growing interest to metformin in areas beyond the limits of diabetology serves as a stimulus for further evaluation of its effectiveness as a potential modulator of cancer morbidity and obesity epidemic. Gradually detectable differences in the intensity of these effects of the drug can be explai...

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Format: Article
Language:English
Published: Endocrinology Research Centre 2012-06-01
Series:Ожирение и метаболизм
Subjects:
Online Access:https://endojournals.ru/index.php/omet/article/view/6540
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spelling doaj-fc0be3e415ea40338aafd0a639545cc32021-10-02T16:10:11ZengEndocrinology Research CentreОжирение и метаболизм2071-87132306-55242012-06-0192111610.14341/omet2012211-166400Variable evidence on metformin efficiency as weight-reducing and antiblastomogenic agent: causes and consequencesThe growing interest to metformin in areas beyond the limits of diabetology serves as a stimulus for further evaluation of its effectiveness as a potential modulator of cancer morbidity and obesity epidemic. Gradually detectable differences in the intensity of these effects of the drug can be explained by an insufficient number of randomized trials, differences in the control groups (reference points), gender, age, pharmacogenetic and other factors, the study of which collectively promised to increase the likelihood of more favorable clinical effects of metformin and other antidiabetic biguanides in discussed areas.https://endojournals.ru/index.php/omet/article/view/6540metforminobesitycancer morbiditymodifying factors
collection DOAJ
language English
format Article
sources DOAJ
title Variable evidence on metformin efficiency as weight-reducing and antiblastomogenic agent: causes and consequences
spellingShingle Variable evidence on metformin efficiency as weight-reducing and antiblastomogenic agent: causes and consequences
Ожирение и метаболизм
metformin
obesity
cancer morbidity
modifying factors
title_short Variable evidence on metformin efficiency as weight-reducing and antiblastomogenic agent: causes and consequences
title_full Variable evidence on metformin efficiency as weight-reducing and antiblastomogenic agent: causes and consequences
title_fullStr Variable evidence on metformin efficiency as weight-reducing and antiblastomogenic agent: causes and consequences
title_full_unstemmed Variable evidence on metformin efficiency as weight-reducing and antiblastomogenic agent: causes and consequences
title_sort variable evidence on metformin efficiency as weight-reducing and antiblastomogenic agent: causes and consequences
publisher Endocrinology Research Centre
series Ожирение и метаболизм
issn 2071-8713
2306-5524
publishDate 2012-06-01
description The growing interest to metformin in areas beyond the limits of diabetology serves as a stimulus for further evaluation of its effectiveness as a potential modulator of cancer morbidity and obesity epidemic. Gradually detectable differences in the intensity of these effects of the drug can be explained by an insufficient number of randomized trials, differences in the control groups (reference points), gender, age, pharmacogenetic and other factors, the study of which collectively promised to increase the likelihood of more favorable clinical effects of metformin and other antidiabetic biguanides in discussed areas.
topic metformin
obesity
cancer morbidity
modifying factors
url https://endojournals.ru/index.php/omet/article/view/6540
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