Endocrine disruptors and congenital anomalies

The specialized literature was reviewed concerning the suspected increasing secular trends in the frequency of female births, male genital congenital anomalies, abnormal sperm counts, and testicular cancer. Although no risk factors could be identified yet, the observed sex ratio decline during the l...

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Main Authors: Mônica Rittler, Eduardo E. Castilla
Format: Article
Language:English
Published: Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
Series:Cadernos de Saúde Pública
Subjects:
Online Access:http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200006&lng=en&tlng=en
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spelling doaj-fc16cbf4c01544bab3f265b1b98fb29f2020-11-25T03:25:22ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública0102-311X1678-4464182421428S0102-311X2002000200006Endocrine disruptors and congenital anomaliesMônica Rittler0Eduardo E. Castilla1Hospital Materno Infantil Ramon SardáFundação Oswaldo CruzThe specialized literature was reviewed concerning the suspected increasing secular trends in the frequency of female births, male genital congenital anomalies, abnormal sperm counts, and testicular cancer. Although no risk factors could be identified yet, the observed sex ratio decline during the last decades has been considered to be an effect of certain pollutants on normal hormone activity, and human reproductive development. Reported increasing trends in the frequencies of hypospadias and cryptorchidism are very difficult to be interpreted due to the large variability in the registered frequency of these malformations due to operational as well as biological reasons.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200006&lng=en&tlng=ensex ratiohypospadiacryptorchidismtesticular neoplasmsendocrine disruptors
collection DOAJ
language English
format Article
sources DOAJ
author Mônica Rittler
Eduardo E. Castilla
spellingShingle Mônica Rittler
Eduardo E. Castilla
Endocrine disruptors and congenital anomalies
Cadernos de Saúde Pública
sex ratio
hypospadia
cryptorchidism
testicular neoplasms
endocrine disruptors
author_facet Mônica Rittler
Eduardo E. Castilla
author_sort Mônica Rittler
title Endocrine disruptors and congenital anomalies
title_short Endocrine disruptors and congenital anomalies
title_full Endocrine disruptors and congenital anomalies
title_fullStr Endocrine disruptors and congenital anomalies
title_full_unstemmed Endocrine disruptors and congenital anomalies
title_sort endocrine disruptors and congenital anomalies
publisher Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
series Cadernos de Saúde Pública
issn 0102-311X
1678-4464
description The specialized literature was reviewed concerning the suspected increasing secular trends in the frequency of female births, male genital congenital anomalies, abnormal sperm counts, and testicular cancer. Although no risk factors could be identified yet, the observed sex ratio decline during the last decades has been considered to be an effect of certain pollutants on normal hormone activity, and human reproductive development. Reported increasing trends in the frequencies of hypospadias and cryptorchidism are very difficult to be interpreted due to the large variability in the registered frequency of these malformations due to operational as well as biological reasons.
topic sex ratio
hypospadia
cryptorchidism
testicular neoplasms
endocrine disruptors
url http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200006&lng=en&tlng=en
work_keys_str_mv AT monicarittler endocrinedisruptorsandcongenitalanomalies
AT eduardoecastilla endocrinedisruptorsandcongenitalanomalies
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