Endocrine disruptors and congenital anomalies
The specialized literature was reviewed concerning the suspected increasing secular trends in the frequency of female births, male genital congenital anomalies, abnormal sperm counts, and testicular cancer. Although no risk factors could be identified yet, the observed sex ratio decline during the l...
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doaj-fc16cbf4c01544bab3f265b1b98fb29f2020-11-25T03:25:22ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública0102-311X1678-4464182421428S0102-311X2002000200006Endocrine disruptors and congenital anomaliesMônica Rittler0Eduardo E. Castilla1Hospital Materno Infantil Ramon SardáFundação Oswaldo CruzThe specialized literature was reviewed concerning the suspected increasing secular trends in the frequency of female births, male genital congenital anomalies, abnormal sperm counts, and testicular cancer. Although no risk factors could be identified yet, the observed sex ratio decline during the last decades has been considered to be an effect of certain pollutants on normal hormone activity, and human reproductive development. Reported increasing trends in the frequencies of hypospadias and cryptorchidism are very difficult to be interpreted due to the large variability in the registered frequency of these malformations due to operational as well as biological reasons.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200006&lng=en&tlng=ensex ratiohypospadiacryptorchidismtesticular neoplasmsendocrine disruptors |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mônica Rittler Eduardo E. Castilla |
spellingShingle |
Mônica Rittler Eduardo E. Castilla Endocrine disruptors and congenital anomalies Cadernos de Saúde Pública sex ratio hypospadia cryptorchidism testicular neoplasms endocrine disruptors |
author_facet |
Mônica Rittler Eduardo E. Castilla |
author_sort |
Mônica Rittler |
title |
Endocrine disruptors and congenital anomalies |
title_short |
Endocrine disruptors and congenital anomalies |
title_full |
Endocrine disruptors and congenital anomalies |
title_fullStr |
Endocrine disruptors and congenital anomalies |
title_full_unstemmed |
Endocrine disruptors and congenital anomalies |
title_sort |
endocrine disruptors and congenital anomalies |
publisher |
Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz |
series |
Cadernos de Saúde Pública |
issn |
0102-311X 1678-4464 |
description |
The specialized literature was reviewed concerning the suspected increasing secular trends in the frequency of female births, male genital congenital anomalies, abnormal sperm counts, and testicular cancer. Although no risk factors could be identified yet, the observed sex ratio decline during the last decades has been considered to be an effect of certain pollutants on normal hormone activity, and human reproductive development. Reported increasing trends in the frequencies of hypospadias and cryptorchidism are very difficult to be interpreted due to the large variability in the registered frequency of these malformations due to operational as well as biological reasons. |
topic |
sex ratio hypospadia cryptorchidism testicular neoplasms endocrine disruptors |
url |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000200006&lng=en&tlng=en |
work_keys_str_mv |
AT monicarittler endocrinedisruptorsandcongenitalanomalies AT eduardoecastilla endocrinedisruptorsandcongenitalanomalies |
_version_ |
1724597272671420416 |