Plasma Small Extracellular Vesicles Derived miR-21-5p and miR-92a-3p as Potential Biomarkers for Hepatocellular Carcinoma Screening

Plasma Small Extracellular Vesicles Derived miR-21-5p and miR-92a-3p as Potential Biomarkers for Hepatocellular Carcinoma Screening

IntroductionLiquid biopsy using circulating microvesicles and exosomes is emerging as a new diagnostic tool that could improve hepatocellular carcinoma (HCC) early diagnosis and screening protocols. Our study aimed to investigate the utility of plasma exosomal miR-21-5p and miR-92-3p for HCC diagnos...

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Bibliographic Details
Main Authors: Andrei Sorop, Razvan Iacob, Speranta Iacob, Diana Constantinescu, Leona Chitoiu, Tudor Emanuel Fertig, Anca Dinischiotu, Mihaela Chivu-Economescu, Nicolae Bacalbasa, Lorand Savu, Liliana Gheorghe, Simona Dima, Irinel Popescu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Genetics
Subjects:
exosomes
microRNA
serum biomarkers
hepatocellular carcinoma
screening
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00712/full

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