Cryo-EM insight into the structure of MTOR complex 1 and its interactions with Rheb and substrates [version 1; referees: 3 approved]
The mechanistic target of rapamycin (MTOR) is a giant protein kinase that, together with the accessory proteins Raptor and mLst8, forms a complex of over 1 MDa known as MTOR complex 1 (MTORC1). MTORC1, through its protein kinase activity, controls the accretion of cell mass through the regulation of...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2019-01-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-14/v1 |