Hearing impairment in patients with tuberculosis from Northeast Brazil Alteração auditiva em pacientes com tuberculose no nordeste do Brasil

The aim of this paper is to describe the auditory profile of subjects who were given streptomycin treatment for tuberculosis in the years 2000 and 2001, in Recife, Northeast Brazil. The Injury Notification Database at the Municipal Department of Health was consulted and 78 individuals who had been o...

Full description

Bibliographic Details
Main Authors: Maria Luiza Lopes Timóteo de Lima, Fábio Lessa, Ana Maria Aguiar-Santos, Zulma Medeiros
Format: Article
Language:English
Published: Universidade de São Paulo 2006-04-01
Series:Revista do Instituto de Medicina Tropical de São Paulo
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652006000200008
id doaj-fc339711de19460599615e56d633c5ab
record_format Article
spelling doaj-fc339711de19460599615e56d633c5ab2020-11-24T23:03:30ZengUniversidade de São PauloRevista do Instituto de Medicina Tropical de São Paulo0036-46651678-99462006-04-014829910210.1590/S0036-46652006000200008Hearing impairment in patients with tuberculosis from Northeast Brazil Alteração auditiva em pacientes com tuberculose no nordeste do BrasilMaria Luiza Lopes Timóteo de LimaFábio LessaAna Maria Aguiar-SantosZulma MedeirosThe aim of this paper is to describe the auditory profile of subjects who were given streptomycin treatment for tuberculosis in the years 2000 and 2001, in Recife, Northeast Brazil. The Injury Notification Database at the Municipal Department of Health was consulted and 78 individuals who had been on streptomycin during the period under study were selected. Forty-two individuals were excluded, of whom five were over 59 years of age and two were under 18 years. Nineteen turned out to be deceased, 13 could not be found, two were serving prison terms and one refused to participate. As a result, only 36 subjects participated in the study. These 36 individuals were interviewed and underwent meatoscopy and audiometry. The mean age of the group under study was 38.8 years old and males predominated (79.4%). Twenty-seven patients (75%) showed hearing impairment, the bilateral sensorineural type (63.9%) being the most frequent, mainly affecting the high frequencies over 4000 Hz. In the light of findings showing a high percentage of hearing impairment complaints among users of streptomycin, this issue seems to warrant an in-depth investigation, as does the implementation of an auditory follow-up routine for patients undergoing such chemotherapy for tuberculosis.<br>Este trabalho teve por objetivo descrever o perfil auditivo de pessoas que realizaram tratamento para tuberculose com estreptomicina em Recife nos anos de 2000 e 2001. Para tal foi utilizado o banco de dados do Sistema de Informação de Agravos de Notificação, fornecido pela Secretária de Saúde deste município, sendo selecionadas 78 pessoas que usaram a droga no período em estudo. Do total de pacientes selecionados sete eram menores de 18 anos ou maiores de 58 anos, 19 haviam falecido, 13 não foram localizados, dois eram presidiários, um negou-se a participar, restando, pois 36 indivíduos que puderam ser submetidos a uma entrevista, a meatoscopia e a audiometria. No grupo estudado predominou o sexo masculino (79,4%) e a média das idades era de 38,8 anos. Dos 36 pacientes, 27 (75,0%) apresentaram alteração auditiva, sendo a mais freqüente a sensório-neural bilateral (63,9%), com predomínio de freqüências agudas, a partir de 4000 Hz. Os achados com elevados percentuais de alteração auditiva entre os usuários de estreptomicina, apontam para a necessidade de aprofundamento deste tema em outros estudos, e também sugerem a necessidade de estruturação de um sistema de monitoramento auditivo para a população de pacientes submetidos a esse quimioterápico no tratamento para tuberculose.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652006000200008TuberculosisHearing impairmentOtotoxicity
collection DOAJ
language English
format Article
sources DOAJ
author Maria Luiza Lopes Timóteo de Lima
Fábio Lessa
Ana Maria Aguiar-Santos
Zulma Medeiros
spellingShingle Maria Luiza Lopes Timóteo de Lima
Fábio Lessa
Ana Maria Aguiar-Santos
Zulma Medeiros
Hearing impairment in patients with tuberculosis from Northeast Brazil Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
Revista do Instituto de Medicina Tropical de São Paulo
Tuberculosis
Hearing impairment
Ototoxicity
author_facet Maria Luiza Lopes Timóteo de Lima
Fábio Lessa
Ana Maria Aguiar-Santos
Zulma Medeiros
author_sort Maria Luiza Lopes Timóteo de Lima
title Hearing impairment in patients with tuberculosis from Northeast Brazil Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
title_short Hearing impairment in patients with tuberculosis from Northeast Brazil Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
title_full Hearing impairment in patients with tuberculosis from Northeast Brazil Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
title_fullStr Hearing impairment in patients with tuberculosis from Northeast Brazil Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
title_full_unstemmed Hearing impairment in patients with tuberculosis from Northeast Brazil Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
title_sort hearing impairment in patients with tuberculosis from northeast brazil alteração auditiva em pacientes com tuberculose no nordeste do brasil
publisher Universidade de São Paulo
series Revista do Instituto de Medicina Tropical de São Paulo
issn 0036-4665
1678-9946
publishDate 2006-04-01
description The aim of this paper is to describe the auditory profile of subjects who were given streptomycin treatment for tuberculosis in the years 2000 and 2001, in Recife, Northeast Brazil. The Injury Notification Database at the Municipal Department of Health was consulted and 78 individuals who had been on streptomycin during the period under study were selected. Forty-two individuals were excluded, of whom five were over 59 years of age and two were under 18 years. Nineteen turned out to be deceased, 13 could not be found, two were serving prison terms and one refused to participate. As a result, only 36 subjects participated in the study. These 36 individuals were interviewed and underwent meatoscopy and audiometry. The mean age of the group under study was 38.8 years old and males predominated (79.4%). Twenty-seven patients (75%) showed hearing impairment, the bilateral sensorineural type (63.9%) being the most frequent, mainly affecting the high frequencies over 4000 Hz. In the light of findings showing a high percentage of hearing impairment complaints among users of streptomycin, this issue seems to warrant an in-depth investigation, as does the implementation of an auditory follow-up routine for patients undergoing such chemotherapy for tuberculosis.<br>Este trabalho teve por objetivo descrever o perfil auditivo de pessoas que realizaram tratamento para tuberculose com estreptomicina em Recife nos anos de 2000 e 2001. Para tal foi utilizado o banco de dados do Sistema de Informação de Agravos de Notificação, fornecido pela Secretária de Saúde deste município, sendo selecionadas 78 pessoas que usaram a droga no período em estudo. Do total de pacientes selecionados sete eram menores de 18 anos ou maiores de 58 anos, 19 haviam falecido, 13 não foram localizados, dois eram presidiários, um negou-se a participar, restando, pois 36 indivíduos que puderam ser submetidos a uma entrevista, a meatoscopia e a audiometria. No grupo estudado predominou o sexo masculino (79,4%) e a média das idades era de 38,8 anos. Dos 36 pacientes, 27 (75,0%) apresentaram alteração auditiva, sendo a mais freqüente a sensório-neural bilateral (63,9%), com predomínio de freqüências agudas, a partir de 4000 Hz. Os achados com elevados percentuais de alteração auditiva entre os usuários de estreptomicina, apontam para a necessidade de aprofundamento deste tema em outros estudos, e também sugerem a necessidade de estruturação de um sistema de monitoramento auditivo para a população de pacientes submetidos a esse quimioterápico no tratamento para tuberculose.
topic Tuberculosis
Hearing impairment
Ototoxicity
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652006000200008
work_keys_str_mv AT marialuizalopestimoteodelima hearingimpairmentinpatientswithtuberculosisfromnortheastbrazilalteracaoauditivaempacientescomtuberculosenonordestedobrasil
AT fabiolessa hearingimpairmentinpatientswithtuberculosisfromnortheastbrazilalteracaoauditivaempacientescomtuberculosenonordestedobrasil
AT anamariaaguiarsantos hearingimpairmentinpatientswithtuberculosisfromnortheastbrazilalteracaoauditivaempacientescomtuberculosenonordestedobrasil
AT zulmamedeiros hearingimpairmentinpatientswithtuberculosisfromnortheastbrazilalteracaoauditivaempacientescomtuberculosenonordestedobrasil
_version_ 1716375522337882112